机构

• 上海药物研究所 [38]
• 天津工业生物技术研究... [3]
• 大连化学物理研究所 [1]
• 水生生物研究所 [1]
• 过程工程研究所 [1]
• 武汉植物园 [1]
• 更多

采集方式

• OAI收割 [46]

内容类型

• 期刊论文 [46]

发表日期

• 2023 [3]
• 2022 [4]
• 2021 [8]
• 2020 [5]
• 2019 [3]
• 2018 [2]
• 更多

学科主题

• Toxicology [1]
• 物理化学 [1]

筛选

浏览/检索结果: 共46条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14 作者:  He, Fei;  Jiang, Haowen;  Peng, Chang;  Wang, Tingting;  Xiao, Rongrong   |  收藏  |  浏览/下载：61/0  |  提交时间：2023/10/17 Glucuronyl C5-epimerase  Growth differentiation factor-15  Obesity  Energy expenditure  Ubiquitination   Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3Ka) 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023, 卷号: 1878, 期号: 5, 页码: 6 作者:  Vogt, Peter K.;  Hart, Jonathan R.;  Yang, Su;  Zhou, Qingtong;  Yang, Dehua   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 Phosphoinositide 3-kinase  BYL-719  Nanobody  CXMS  Mutants   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割 CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17 作者:  Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 46, 页码: 11 作者:  Liu, Xiao;  Zhou, Qingtong;  Hart, Jonathan R.;  Xu, Yingna;  Yang, Su   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 phosphoinositide 3-kinase (PI3K)  mass spectrometry  mutants   Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations br 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858 作者:  Chen, Hao;  Lai, Mengzhen;  Zhang, Tao;  Chen, Yuqing;  Tong, Linjiang   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7 作者:  Li, Shan   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/15 Epidermal Growth Factor Receptor (EGFR)  Resistant Mutation  C797S  Antitumor   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness 期刊论文  OAI收割 CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732 作者:  Yang, Lin;  Sun, Jingya;  Li, Meiqian;  Long, Yiming;  Zhang, Dianzheng   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04 A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文  OAI收割 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/12/01