中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
Lindenane sesquiterpenoid dimers from
Chloranthus
japonicus
improve LDL uptake by regulating PCSK9 and LDLR
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 142, 页码: 13
作者:
Guo, Pengju
;
Chen, Tong
;
Hu, Xianggang
;
Duan, Yelin
;
Zheng, Liu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/16
Chloranthus japonicas
Lindenane sesquiterpenoid dimers
PCSK9
LDLR
Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 11
作者:
Yang, Shuangshuang
;
Fan, Lei
;
Zhang, Rui
;
Song, Chenghuan
;
Shi, Jiyun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Alzheimer's disease
Brain-derived neurotrophic factor
Histone acetylation
Smilagenin
A novel peptidoglycan isolated from Semiaquilegia adoxoides inhibits A beta(42) production via activating autophagy
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 169, 页码: 11
作者:
Li, Saijuan
;
Wu, Fangge
;
Gao, Pengcheng
;
Jin, Can
;
Wang, Yuyong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Semiaquilegia adoxoides
Amyloid beta
Autophagy
Peptidoglycan
Alzheimer's disease
Why does SLIPS inhibit P.aeruginosa initial adhesion in static condition?
期刊论文
OAI收割
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2023, 卷号: 124, 页码: 532-538
作者:
Shen, Yuanyuan
;
Sun, Yihan
;
Wang, Peng
;
Zhang, Dun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/07
Slippery liquid-infused porous surface
(SLIPS)
Initial adhesion
Static condition
RNA sequencing (RNA-seq)
Type II secretion system (T2SS)
Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-beta 1/Smad Signaling and Activation of Nrf2/HO-1 Signaling
期刊论文
OAI收割
STEM CELLS AND DEVELOPMENT, 2023, 页码: 14
作者:
Liu, Wenjing
;
Wu, Jiajun
;
Cao, Huiying
;
Ma, Chen
;
Wu, Zhitao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
hepatic stellate cell activation
liver fibrosis
extracellular vesicles
human-induced hepatocyte
TGF-beta 1/Smad pathway
Nrf2/HO-1 pathway
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into 8-position to the carboxylic acid
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115267
作者:
Chen, Cheng
;
Guo, Shi-Meng
;
Sun, Yuanjun
;
Li, He
;
Hu, Nan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
GPR40
Glucose-stimulated insulin secretion
Type 2 diabetes mellitus
Lipophilicity
Liver safety
Three-in-one pharmacophore
2-(phenylsulfinyl)acetic acid
Engineering a HER2-CAR-NK Cell Secreting Soluble Programmed Cell Death Protein with Superior Antitumor Efficacy
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 7, 页码: 6843
作者:
Xia, Wenjiao
;
Chen, Jiaxin
;
Hou, Wenqing
;
Chen, Junsheng
;
Xiong, Ying
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
breast cancers
cytotherapy
chimeric antigen receptor
NK cells
sPD-1