中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共217条,第1-10条 帮助

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Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:  
Lin, Ting-ting;  Xiong, Wei;  Chen, Gui-hua;  He, Yang;  Long, Li
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/01/26
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation 期刊论文  OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:  
Xiao, Yufeng;  Hale, Seth;  Awasthee, Nikee;  Meng, Chengcheng;  Zhang, Xuan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/01/16
Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming 期刊论文  OAI收割
DIABETES, 2023, 卷号: 72, 期号: 11, 页码: 24
作者:  
Pan, Xiaowen;  Ye, Lingxia;  Guo, Xiaozhen;  Wang, Weihua;  Zhang, Ziyin
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/03/25
Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease 期刊论文  OAI收割
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 11
作者:  
Yang, Shuangshuang;  Fan, Lei;  Zhang, Rui;  Song, Chenghuan;  Shi, Jiyun
  |  收藏  |  浏览/下载:12/0  |  提交时间:2023/10/17
HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation 期刊论文  OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 17
作者:  
Li, Jialun;  Lu, Lu;  Liu, Lingling;  Ren, Xuelian;  Chen, Jiwei
  |  收藏  |  浏览/下载:30/0  |  提交时间:2023/10/17
GRP/GRPR enhances alcohol-associated liver injury through the IRF1-mediated Caspase-1 inflammasome and NOX2-dependent ROS pathway 期刊论文  OAI收割
HEPATOLOGY, 2023, 页码: 17
作者:  
Li, Haidi;  Chen, Xin;  Xu, Jiejie;  Zhu, Lin;  Li, Chao
  |  收藏  |  浏览/下载:144/0  |  提交时间:2024/02/27
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:  
Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin
  |  收藏  |  浏览/下载:24/0  |  提交时间:2023/10/17
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:  
Guo, Siqi;  Jia, Tongguan;  Xu, Xiaoming;  Yang, Feng;  Xiao, Senhao
  |  收藏  |  浏览/下载:20/0  |  提交时间:2023/04/10
Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression 期刊论文  OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 2, 页码: 692-704
作者:  
Hu, Zonglong;  Wei, Fan;  Su, Yi;  Wang, Yafang;  Shen, Yanyan
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/03/27
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma 期刊论文  OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:  
Yang, Zijian;  Yan, Cong;  Ma, Jiaqiang;  Peng, Panpan;  Ren, Xuelian
  |  收藏  |  浏览/下载:18/0  |  提交时间:2023/04/10