中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [117]
过程工程研究所 [47]
上海生物化学与细胞... [45]
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期刊论文 [578]
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Cell Biol... [27]
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TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Co-delivering irinotecan and imiquimod by pH-responsive micelle amplifies anti-tumor immunity against colorectal cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 648, 页码: 14
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
Colorectal cancer
Irinotecan
Imiquimod
Micelle
Immune response
Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
OAI收割
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy