中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [23]
生物物理研究所 [1]
大连化学物理研究所 [1]
武汉病毒研究所 [1]
自动化研究所 [1]
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OAI收割 [26]
iSwitch采集 [1]
内容类型
期刊论文 [27]
发表日期
2024 [1]
2023 [1]
2022 [1]
2021 [1]
2020 [4]
2019 [2]
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学科主题
Oncology [1]
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浏览/检索结果:
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
An Integrative Proteome-Based Pharmacologic Characterization and Therapeutic Strategy Exploration of SAHA in Solid Malignancies br
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2022, 卷号: 21, 期号: 4, 页码: 953-964
作者:
Liu, Quan
;
Hao, Bingbing
;
Zhang, Mingya
;
Liu, Zhiwei
;
Huang, Yuqi
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
proteomics
SAHA
2-deoxy-D-glucose
new combination strategy
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
期刊论文
OAI收割
BIOMATERIALS SCIENCE, 2020, 卷号: 8, 期号: 24, 页码: 7166-7176
作者:
Tu, Bin
;
He, Yang
;
Chen, Binfan
;
Wang, Yonghui
;
Gao, Yanrong
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
;
Ru, Hong-bo
;
Bao, Bin
;
Yu, Jia-hui
;
Li, Jia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8, 页码: 8
作者:
Tu, Bin
;
Zhang, Meng
;
Liu, Tuanbing
;
Huang, Yongzhuo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
Histone deacetylase inhibitors (HDACi)
nanotechnology
nanomedicine
cancer therapy
solid tumor
targeting drug delivery
combination therapy
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
期刊论文
OAI收割
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:
Liu, Shuangxi
;
Hu, Zonglong
;
Zhang, Qiumeng
;
Zhu, Qiwen
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Identification of HDAC9 as a viable therapeutic target for the treatment of gastric cancer
期刊论文
OAI收割
EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, 卷号: 51, 页码: 15
作者:
Xiong, Kai
;
Zhang, Hejun
;
Du, Yang
;
Tian, Jie
;
Ding, Shigang
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/12/16
Synthesis and biological evaluation of paclitaxel and vorinostat co-prodrugs for overcoming drug resistance in cancer therapy in vitro
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 7, 页码: 1405-1413
作者:
Liu, Shuangxi
;
Zhang, Kaili
;
Zhu, Qiwen
;
Shen, Qianqian
;
Zhang, Qiumeng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
PTX
SAHA
Co-prodrug
Nanomicelles