中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
金属研究所 [2]
上海生物化学与细胞生... [2]
昆明植物研究所 [1]
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OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2018 [1]
2013 [3]
2012 [1]
2011 [1]
2010 [2]
2007 [1]
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学科主题
Cell Biolo... [1]
Research &... [1]
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Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
OAI收割
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both beta-Amyloid Production and Clearance
期刊论文
OAI收割
JOURNAL OF NEUROSCIENCE, 2013, 卷号: 33, 期号: 32, 页码: 13138-13149
作者:
Zhu, Zhiyuan
;
Yan, Jianming
;
Jiang, Wei
;
Yao, Xin-gang
;
Chen, Jing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621
作者:
Li Xiaoman
;
Hong Lin
;
Coughlan Kathleen
;
Wang Liang
;
Cao Liu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/02/02
AMYLOID PRECURSOR PROTEIN
BETA-SECRETASE BACE1
GATED SODIUM-CHANNELS
CLEAVING ENZYME
GGA PROTEINS
ASPARTYL PROTEASE
NEURONAL-ACTIVITY
GENETIC DELETION
CYTOSOLIC DOMAIN
ALPHA-SECRETASE
memapsin 2
BACE1
beta-amyloid
subsite specificity
activity prediction
Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621
作者:
Li Xiaoman
;
Hong Lin
;
Coughlan Kathleen
;
Wang Liang
;
Cao Liu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2021/02/02
AMYLOID PRECURSOR PROTEIN
BETA-SECRETASE BACE1
GATED SODIUM-CHANNELS
CLEAVING ENZYME
GGA PROTEINS
ASPARTYL PROTEASE
NEURONAL-ACTIVITY
GENETIC DELETION
CYTOSOLIC DOMAIN
ALPHA-SECRETASE
memapsin 2
BACE1
beta-amyloid
subsite specificity
activity prediction
Huperzine A Alleviates Synaptic Deficits and Modulates Amyloidogenic and Nonamyloidogenic Pathways in APPswe/PS1dE9 Transgenic Mice
期刊论文
OAI收割
JOURNAL OF NEUROSCIENCE RESEARCH, 2012, 卷号: 90, 期号: 2, 页码: 508-517
作者:
Wang, Ying
;
Tang, Xi Can
;
Zhang, Hai Yan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
beta-amyloid
ADAM10
BACE1
Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice
期刊论文
OAI收割
BIOSCIENCE TRENDS, 2011, 卷号: 5, 期号: 3, 页码: 129-138
作者:
Mishra, Manisha
;
Huang, Junjie
;
Lee, Yin Yeng
;
Chua, Doreen See Kin
;
Lin, Xiaoyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/08/17
Alzheimer's disease
beta-Amyloid precursor protein
Kampo
Neurodegeneration
traditional Chinese medicine
2,2',4'-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice
期刊论文
OAI收割
JOURNAL OF NEUROCHEMISTRY, 2010, 卷号: 114, 期号: 2, 页码: 374-385
作者:
Zhu, Zhiyuan
;
Li, Chenjing
;
Wang, Xu
;
Yang, Zhengyi
;
Chen, Jing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Alzheimer's disease
amyloid-beta
inhibitor
transgenic mice
trihydroxychalcone
beta-site amyloid precursor protein-cleaving enzyme 1 (beta-secretase)
The enhancement of amyloid precursor protein and beta-site amyloid cleavage enzyme 1 interaction: Amyloid-beta production with aging
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2010, 卷号: 25, 期号: 3, 页码: 401-407
作者:
Zou, L
;
Yang, RX
;
Zhang, PH
;
Da, Y
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2015/07/22
amyloid precursor protein
beta-site amyloid cleavage enzyme 1
amyloid-beta
aging
interaction
Receptor tyrosine kinases positively regulate BACE activity and Amyloid-beta production through enhancing BACE internalization
期刊论文
OAI收割
CELL RESEARCH, 2007, 卷号: 17, 期号: 5, 页码: 389-401
作者:
Zou, L
;
Wang, Z
;
Shen, L
;
Bao, GB
;
Wang, T
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2015/07/22
beta-site APP cleavage enzyme
RTK
Amyloid-beta
Src
Studies of secretase inhibitors of amyloid-ss protein
期刊论文
OAI收割
PROGRESS IN CHEMISTRY, 2004, 卷号: 16, 期号: 5, 页码: 791-796
作者:
Song, F
;
He, XC
;
Bai, DL
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
A ss
ss secretase
inhibitors
AD