机构

• 上海药物研究所 [31]
• 昆明植物研究所 [2]
• 长春应用化学研究所 [2]
• 昆明动物研究所 [2]
• 西双版纳热带植物园 [1]
• 武汉病毒研究所 [1]
• 更多

采集方式

• OAI收割 [38]
• iSwitch采集 [2]

内容类型

• 期刊论文 [40]

发表日期

• 2021 [2]
• 2019 [2]
• 2018 [1]
• 2016 [1]
• 2015 [1]
• 2013 [3]
• 更多

学科主题

• Cell Biolo... [1]
• Food Scien... [1]
• Neuroscien... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共40条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain 期刊论文  OAI收割 ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 页码: 13 作者:  Guo, Runcong;  Zhou, Lei;  Chen, Xiaoyan   |  收藏  |  浏览/下载：17/0  |  提交时间：2021/11/04 DESI  Mass spectrometry imaging  Fluoropezil (DC20)  Brain distribution  Optimization strategy   Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855 作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166 作者:  Liu, Guangpu;  Jiao, Yang;  Lin, Yongqiang;  Hao, Haifang;  Dou, Yanli   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 selective acetylcholinesterase inhibitor  amyloid beta aggregation  neuroprotectant  molecular docking  molecular dynamics simulation   Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文  OAI收割 MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21 作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 selective BChE inhibitor  virtual screening  structural optimization  molecular dynamics  anti-A beta aggregation   Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530 作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Song, Jia-Li;  Wang, Yin-Yin   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 AChE inhibitor  Pharmacophore model  Molecular docking  Anti-A aggregation  Neuroprotective activity   Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345 作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong   |  收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Alzheimer's disease  drug repositioning  dual-target inhibitor  AChE inhibition  PDE5 inhibition   Colorimetric determination of the activity of acetylcholinesterase and its inhibitors by exploiting the iodide-catalyzed oxidation of 3,3',5,5'-tetramethylbenzidine by hydrogen peroxide 期刊论文  iSwitch采集 Microchimica acta, 2016, 卷号: 183, 期号: 9, 页码: 2589-2595 作者:   收藏  |  浏览/下载：69/0  |  提交时间：2019/05/09 Enzyme activity assay  Enzyme inhibition  Neostigmine  Ache  Tmb  Thiocholine  Chromogenic reaction   Gold nanoclusters-Cu2+ ensemble-based fluorescence turn-on and real-time assay for acetylcholinesterase activity and inhibitor screening 期刊论文  OAI收割 biosensors & bioelectronics, 2015, 卷号: 74, 页码: 177-182 作者:  Sun,Jian;  Yang,Xiurong 收藏  |  浏览/下载：123/0  |  提交时间：2016/05/04 SELECTIVE DETECTION  CHOLINESTERASE ACTIVITY  ENHANCED FLUORESCENCE  METAL NANOCLUSTERS  RAPID SYNTHESIS  QUANTUM DOTS  PROTEIN  PROBE  NANOPARTICLES  ENZYME   Two New Triterpenoids from Gelsemium elegans and Aglaia odorata 期刊论文  OAI收割 NATURAL PRODUCT COMMUNICATIONS, 2013, 卷号: 8, 期号: 10, 页码: 1373-1376 作者:  Liu, Bing;  Yang, Lin;  Xu, You-Kai;  Liao, Shang-Gao;  Luo, Huai-Rong 收藏  |  浏览/下载：21/0  |  提交时间：2014/01/13 Gelsemium elegans  Aglaia odorata  Eleganoside A  Odoratanone A  AChE/BchE   Two New Triterpenoids from Gelsemium elegans and Aglaia odorata 期刊论文  OAI收割 NATURAL PRODUCT COMMUNICATIONS, 2013, 卷号: 8, 期号: 10, 页码: 1373-1376 作者:  (Xu, You-Kai 收藏  |  浏览/下载：15/0  |  提交时间：2013/11/28 Gelsemium elegans  Aglaia odorata  Eleganoside A  Odoratanone A  AChE/BchE