中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
中国科学院大学 [2]
采集方式
OAI收割 [7]
iSwitch采集 [2]
内容类型
期刊论文 [9]
发表日期
2021 [4]
2019 [1]
2016 [1]
2014 [2]
2009 [1]
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Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
OAI收割
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Direct Cardiac Actions of the Sodium Glucose Co-Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure-Overload Heart Failure
期刊论文
OAI收割
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2021, 卷号: 10, 期号: 6, 页码: 33
作者:
Li, Xuan
;
Lu, Qingguo
;
Qiu, Yunguang
;
do Carmo, Jussara M.
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
cardiac hypertrophy
cardiac metabolism
cardiomyocytes
sodium glucose cotransporter 2
transverse aortic constriction
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
OAI收割
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
Postnatal developmental changes of the small intestinal villus height, crypt depth and hexose transporter mrna expression in supplemental feeding and grazing goats
期刊论文
iSwitch采集
Small ruminant research, 2016, 卷号: 141, 页码: 106-112
作者:
Li, Hengzhi
;
Ran, Tao
;
He, Zhixiong
;
Yan, Qiongxian
;
Tang, Shaoxun
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/05/09
Villus
Crypt
Hexose transporter
Intestine
Feeding regime
Goat
SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 613-624
作者:
Yan, Pang-ke
;
Zhang, Li-na
;
Feng, Ying
;
Qu, Hui
;
Qin, Li
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
sodium glucose cotransporter 2 (SGLT2)
SHR3824
dapagliflozin
type 2 diabetes mellitus
blood glucose
insulin sensitivity
beta-cell function
shr3824anovelselectiveinhibitorofrenalsodiumglucosecotransporter2exhibitsantidiabeticefficacyinrodentmodels
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 5, 页码: 613
作者:
Yan Pangke
;
Zhang Lina
;
Feng Ying
;
Qu Hui
;
Qin Li
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
BETA-CELL DIFFERENTIATION
IMPROVES GLYCEMIC CONTROL
TYPE-2 DIABETES-MELLITUS
CHRONIC HYPERGLYCEMIA
INSULIN-SECRETION
SGLT-2 INHIBITOR
SKELETAL-MUSCLE
RATS
DAPAGLIFLOZIN
EMPAGLIFLOZIN
sodium glucose cotransporter 2 (SGLT2)
SHR3824
dapagliflozin
type 2 diabetes mellitus
blood glucose
insulin sensitivity
beta-cell function
O-spiro c-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (sglt2) inhibitors
期刊论文
iSwitch采集
Bioorganic & medicinal chemistry letters, 2009, 卷号: 19, 期号: 19, 页码: 5632-5635
作者:
Xu, Baihua
;
Lv, Binhua
;
Feng, Yan
;
Xu, Ge
;
Du, Jiyan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/05/10
Sglt
Spiro
Glucosides