中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
机构
  • 上海药物研究所 [157]
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发表日期
  • 2022 [157]
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浏览/检索结果: 共157条,第1-10条 帮助

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Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:  
Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian
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Chemotherapy-induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin 期刊论文  OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 16
作者:  
Liu, Peng;  Ye, Lichun;  Ren, Yongshen;  Zhao, Guodun;  Zhang, Yun
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Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain 期刊论文  OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:  
Zhang, Yuanwen;  Zheng, Yueming;  Wu, Qingqing;  Tian, Fuyun;  Ma, Chuanjun
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Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:  
Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua
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Insights into divalent cation regulation and G(13)-coupling of orphan receptor GPR35 期刊论文  OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 12
作者:  
Duan, Jia;  Liu, Qiufeng;  Yuan, Qingning;  Ji, Yujie;  Zhu, Shengnan
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The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301 期刊论文  OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:  
Xu, Chi;  Cheng, Yun;  Han, Manman;  Tao, Yimin;  Liu, Jing-Gen
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ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK 期刊论文  OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:  
Song, Peiran;  Bai, Gang;  Chan, Shingpan;  Zhang, Tao;  Tong, Linjiang
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Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha 期刊论文  OAI收割
MOLECULAR CELL, 2022, 卷号: 82, 期号: 24, 页码: 4700-+
作者:  
Zhou, Qi;  Hao, Bingbing;  Cao, Xiaolei;  Gao, Lin;  Yu, Zhenyue
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Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:  
Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue
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Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms 期刊论文  OAI收割
CHEMICAL COMMUNICATIONS, 2022, 页码: 4
作者:  
Li, Jian;  Sun, Jina;  Zhang, Xianglei;  Zhang, Ruxue;  Wang, Qian
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