中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
合肥物质科学研究院 [4]
计算技术研究所 [2]
昆明植物研究所 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2021 [13]
学科主题
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发表日期:2021
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Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution
期刊论文
OAI收割
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:
Wu, Yibo
;
Lai, Xiaoyu
;
Shi, Jimin
;
Tan, Yamin
;
Zhao, Yanmin
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/10
haploidentical
haematopoietic stem cell transplantation
donor selection
donor characteristics
donor age
female to male
Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy
期刊论文
OAI收割
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877
作者:
Hu, Shengquan
;
Liu, Jing
;
Chen, Sikang
;
Gao, Jian
;
Zhou, Yubo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
acute myeloid leukemia
FMS-like tyrosine kinase 3
CovDock
hybrid virtual screening
autodock
Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 12
作者:
Liao, Min
;
Dong, Qiongye
;
Chen, Ruiqing
;
Xu, Liqian
;
Jiang, Yuxuan
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/12/01
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/16
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:
Hu, Chen
;
Zou, Fengming
;
Wang, Aoli
;
Miao, Weili
;
Liang, Qianmao
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/01
TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2 (vol 81, pg 1004, 2020)
期刊论文
OAI收割
DRUG DEVELOPMENT RESEARCH, 2021, 页码: 1
作者:
Niu, Gang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/01
coronavirus
cytokine storm
literature mining
renin
angiotensin system
topic inference
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
OAI收割
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:
Qiu, Xiaqiu
;
Li, Yuanqing
;
Yu, Bin
;
Ren, Jie
;
Huang, Huidan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
CDK9
Antitumor
PROTAC
AML
Degrader