中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [16]
昆明植物研究所 [4]
高能物理研究所 [1]
采集方式
OAI收割 [21]
内容类型
期刊论文 [20]
学位论文 [1]
发表日期
2021 [21]
学科主题
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Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:
Yan, Wenzhong
;
Ling, Lijun
;
Wu, Yiran
;
Yang, Kexin
;
Liu, Ruiquan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/16
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:
Jin, Tingting
;
Xu, Lei
;
Wang, Peipei
;
Hu, Xiaobei
;
Zhang, Runyuan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/16
Myelocytomatosis-Protein Arginine N-Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular Carcinoma
期刊论文
OAI收割
HEPATOLOGY, 2021, 卷号: 74, 期号: 4, 页码: 1932-1951
作者:
Luo, Yuhong
;
Gao, Yuqing
;
Liu, Weiwei
;
Yang, Yuan
;
Jiang, Jie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21
Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 页码: 7
作者:
Qi, Jingjing
;
Zhang, Yan
;
Liu, Qunfang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
Clerodendrum chinense
Natural products
Diterpenoids
Structural elucidation
Antiproliferative activities
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:
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收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/06/11
飞龙掌血化学成分及细胞毒活性研究
学位论文
OAI收割
2021
作者:
陈姗姗
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/20
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking