机构

• 上海药物研究所 [107]

采集方式

• OAI收割 [107]

内容类型

• 期刊论文 [92]
• 项目 [15]

发表日期

• 2024 [1]
• 2023 [25]
• 2022 [30]
• 2021 [29]
• 2020 [22]

学科主题

筛选

浏览/检索结果: 共107条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Xuanbai Chengqi Decoction alleviates acute lung injury by inhibiting NLRP3 inflammasome 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319, 页码: 13 作者:  Wang, Shun;  Lin, Feifei;  Zhang, Chengxi;  Gao, Dan;  Qi, Zhuocao   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/08 Xuanbai Chengqi Decoction  Acute lung injury  NLRP3 inflammasome  Pyroptosis   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Repurposing of Rutan showed effective treatment for COVID-19 disease 期刊论文  OAI收割 FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13 作者:  Salikhov, Shavkat I.;  Abdurakhmonov, Ibrokhim Y.;  Oshchepkova, Yuliya I.;  Ziyavitdinov, Jamolitdin F.;  Berdiev, Nodir Sh.   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 COVID-19  SARS-CoV-2  3CLpro  RdRp  Rhus coriaria  Rutan  clinical trial   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10 作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08 Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9 作者:  Sun, Zengchao;  Wang, Lu;  Li, Lingyun;  Sun, Yili;  Zhang, Daizhou   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 SARS-CoV-2 virus  Receptor -binding domain  Nanobody  Crystal structure  Conservative binding epitope  Bi-paratopic nanobodies   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms   Multi-omics for COVID-19: driving development of therapeutics and vaccines 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 9, 页码: 30 作者:     |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/19 COVID-19  SARS-CoV-2  multi-omics  antibodies  small-molecule drugs  vaccines   Discovery of novel non-peptidic and non-covalent small-molecule 3CL(pro) inhibitors as potential candidate for COVID-19 treatment 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 4 作者:  Jiang, Zhidong;  Feng, Bo;  Zhang, Yumin;  Nie, Tianqing;  Liu, Hong   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Sensitivity-enhanced nanoplasmonic biosensor using direct immobilization of two engineered nanobodies for SARS-CoV-2 spike receptor-binding domain detection 期刊论文  OAI收割 SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 383, 页码: 133575 作者:  Ma, Zhengtai;  Sun, Zengchao;  Lv, Xiaoqing;  Chen, Hongda;  Geng, Yong   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Nanoplasmonics  Biosensor  COVID-19  Nanobody  Immobilization  High -throughput