机构

• 上海药物研究所 [29]

采集方式

• OAI收割 [29]

内容类型

• 期刊论文 [29]

发表日期

• 2024 [1]
• 2023 [2]
• 2021 [1]
• 2020 [3]
• 2019 [1]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共29条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Meta-MolNet: A Cross-Domain Benchmark for Few Examples Drug Discovery 期刊论文  OAI收割 IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 15 作者:  Lv, Qiujie;  Chen, Guanxing;  Yang, Ziduo;  Zhong, Weihe;  Chen, Calvin Yu-Chian   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 Benchmark platform  cross-domain meta-learning  drug discovery  few examples  Meta-MolNet  molecular property   Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy 期刊论文  OAI收割 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877 作者:  Hu, Shengquan;  Liu, Jing;  Chen, Sikang;  Gao, Jian;  Zhou, Yubo   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/06/15 acute myeloid leukemia  FMS-like tyrosine kinase 3  CovDock  hybrid virtual screening  autodock   Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/12/21 Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/12/21 A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11 作者:  Lu, Kang;  Li, Bo;  Zhang, Hui;  Xu, Zhijian;  Song, Dongliang   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 TGF-beta 1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM 期刊论文  OAI收割 EBIOMEDICINE, 2019, 卷号: 42, 页码: 458-469 作者:  Wang, Kuifeng;  Fang, Shanhua;  Liu, Qian;  Gao, Jing;  Wang, Xiaoning   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 Liver fibrosis  TGF-beta 1  MAT2A  p65  SAM   Dynamics revelation of conformational changes and binding modes of heat shock protein 90 induced by inhibitor associations 期刊论文  OAI收割 RSC ADVANCES, 2018, 卷号: 8, 期号: 45, 页码: 25456-25467 作者:  Chen, Jianzhong;  Wang, Jinan;  Lai, Fengbo;  Wang, Wei;  Pang, Laixue   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 Establishment of a reporter gene system for activity detection of hepatocyte nuclear factor 4alpha 期刊论文  OAI收割 Academic Journal of Second Military Medical University, 2017, 卷号: 38, 期号: 9, 页码: 1112-1118 作者:  Sun Bingjie;  Chen Shijie;  Deng Longfei;  Ding Chenhong;  Chen Fei   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Ninjurin 1  hepatocyte nuclear factor 4alpha  Ninjurin 1  reporter gene system  small molecular compound