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Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution 期刊论文  OAI收割
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:  Wu, Yibo;  Lai, Xiaoyu;  Shi, Jimin;  Tan, Yamin;  Zhao, Yanmin
  |  收藏  |  浏览/下载：39/0  |  提交时间：2022/01/10
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli
  |  收藏  |  浏览/下载：39/0  |  提交时间：2021/04/26
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文  OAI收割
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
  |  收藏  |  浏览/下载：76/0  |  提交时间：2019/11/27
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
  |  收藏  |  浏览/下载：34/0  |  提交时间：2020/05/21
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
  |  收藏  |  浏览/下载：40/0  |  提交时间：2019/01/11
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli
  |  收藏  |  浏览/下载：31/0  |  提交时间：2019/12/10
Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
作者:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping
  |  收藏  |  浏览/下载：42/0  |  提交时间：2019/06/17
EpCAM Inhibition Sensitizes Chemoresistant Leukemia to Immune Surveillance 期刊论文  OAI收割
CANCER RESEARCH, 2017, 卷号: 77, 期号: 2, 页码: 482-493
作者:  Zheng, Xiaohu;  Fan, Xiaolei;  Fu, Binqing;  Zheng, Meijuan;  Zhang, Aimei
  |  收藏  |  浏览/下载：38/0  |  提交时间：2018/07/04
Simultaneous inhibition of Vps34 kinase would enhance PI3K delta inhibitor cytotoxicity in the B-cell malignancies 期刊论文  OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 33, 页码: 53515-53525
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Liu, Juanjuan;  Zou, Fengming
收藏  |  浏览/下载：32/0  |  提交时间：2017/11/21
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) 期刊论文  OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:  Liu, Feiyang;  Wang, Beilei;  Wang, Qiang;  Qi, Ziping;  Chen, Cheng
收藏  |  浏览/下载：38/0  |  提交时间：2017/11/21