中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [36]
昆明植物研究所 [6]
生态环境研究中心 [6]
昆明动物研究所 [3]
新疆理化技术研究所 [2]
武汉物理与数学研究所 [2]
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OAI收割 [69]
iSwitch采集 [1]
内容类型
期刊论文 [70]
发表日期
2018 [70]
学科主题
Cell Biolo... [1]
Pharmacolo... [1]
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发表日期:2018
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Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data
期刊论文
OAI收割
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:
Zhang, Lirong
;
Xue, Gaogao
;
Liu, Junjie
;
Li, Qianzhong
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:219/0
  |  
提交时间:2019/01/11
Transcription factor
Histone modification
Co-localization
Dynamics
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:
Wang, Yibing
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/01/08
Evaluation of susceptibility of hiv-1 crf01_ae variants to neutralization by a panel of broadly neutralizing antibodies
期刊论文
iSwitch采集
Archives of virology, 2018, 卷号: 163, 期号: 12, 页码: 3303-3315
作者:
Wang, Hongye
;
Yuan, Ting
;
Li, Tingting
;
Li, Yanpeng
;
Qian, Feng
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/05/08
Restoration of sternness-high tumor cell-mediated suppression of murine dendritic cell activity and inhibition of tumor growth by low molecular weight oyster polysaccharide
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 65, 页码: 221-232
作者:
Zhong, Ming
;
Zhong, Cheng
;
Hu, Pei
;
Cui, Wen
;
Wang, Guanghui
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2019/01/08
Colorectal cancer stem cells
Dendritic cells
TGF-beta
NF-kappa B
Oyster polysaccharide
ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia
期刊论文
OAI收割
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264
作者:
Zhou, Tingting
;
Du, Mengfan
;
Zhao, Tong
;
Quan, Lingling
;
Zhu, Zhiyuan
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
beta cell
apoptosis
glucose-stimulated insulin secretion
T2DM
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:
Peng, Panfeng
;
Chen, Huan
;
Zhu, Ya
;
Wang, Zhilong
;
Li, Jian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 149-165
作者:
Liu, Xiaohua
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Apoptosis
Artemisinin
Bcl-2
Venetoclax
Selectivity
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR
期刊论文
OAI收割
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:
Li, R.
;
Du, Y.
;
Shen, J.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
BTK inhibitors
B-cell malignancies
molecule docking
3D-QSAR
CoMFA
CoMSIA
The aryl hydrocarbon receptor (AhR) activity and DNA-damaging effects of chlorinated polycyclic aromatic hydrocarbons (Cl-PAHs)
期刊论文
OAI收割
CHEMOSPHERE, 2018, 卷号: 211, 页码: 640-647
作者:
Wang, Zijian
;
Rao, Kaifeng
;
Ma, Mei
;
Wang, Donghong
;
Xu, Xiong
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/06/24
Chlorinated PAHs (Cl-PAHs)
Aryl hydrocarbon receptor (AhR)
DNA-Damaging effect
Genotoxicity
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:
Lu, Xiaoyun
;
Zhang, Tao
;
Zhu, Su-Jie
;
Xun, Qiuju
;
Tong, Lingjiang
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2019/01/08
EGFR(C797s)
Clinical resistance
Fourth-generation nhibitors
Monodrug efficacy