中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [98]
上海营养与健康研究... [30]
西北高原生物研究所 [23]
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昆明植物研究所 [16]
合肥物质科学研究院 [14]
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期刊论文 [360]
学位论文 [4]
会议论文 [1]
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2018 [365]
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Cell Biol... [10]
Science & ... [8]
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发表日期:2018
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Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway
期刊论文
OAI收割
Cancer letters, 2018, 卷号: 444, 页码: 45-59
作者:
Xiao, Wenqin
;
Xu, Zhijian
;
Chang, Shuaikang
;
Li, Bo
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
A Phylogenomic Framework and Divergence History of Cephalochordata Amphioxus
期刊论文
OAI收割
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 13
作者:
Zhang, Qi-Lin
;
Zhang, Guan-Ling
;
Yuan, Ming-Long
;
Dong, Zhi-Xiang
;
Li, Hong-Wei
  |  
收藏
  |  
浏览/下载:126/0
  |  
提交时间:2019/05/22
Cephalochordata
Amphioxus
Phylogenomics
Divergence History
Speciation Process
Protein Domains
Evolutionary Genomics
Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux
期刊论文
OAI收割
Acta pharmacologica Sinica, 2018
作者:
Lu, Yu-Ting
;
Xiao, Yu-Feng
;
Li, Yu-Feng
;
Li, Jia
;
Nan, Fa-Jun
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Solution structure of TbCentrin4 from Trypanosoma brucei and its interactions with Ca2+ and other centrins
期刊论文
OAI收割
BIOCHEMICAL JOURNAL, 2018, 卷号: 475, 页码: 3763-3778
作者:
Shan, Fangzhen
;
Ye, Kaiqin
;
Zhang, Jiahai
;
Liao, Shanhui
;
Zhang, Xuecheng
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/12/25
Recent advances in using mass spectrometry for mitochondrial metabolomics and lipidomics - A review
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2018, 卷号: 1037, 页码: 3-12
作者:
Liu, Xinyu
;
Xu, Guowang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/06/20
Mitochondria
Metabolomics
Lipidomics
Mass spectrometry
Metabolic profiling
Four New Depsides Isolated from and Their Significant Nerve-Protective Activities
期刊论文
OAI收割
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 12
作者:
Jin, Qinghao
;
Hu, Xinyi
;
Deng, Yanping
;
Hou, Jinjun
;
Lei, Min
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 48, 页码: 41118-41128
作者:
Chen, Wu
;
Yang, Wen
;
Chen, Pengyu
;
Huang, Yongzhuo
;
Li, Feng
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
disulfiram
copper diethyldithiocarbamate
drug resistance
prostate cancer
nanoparticle
drug delivery
paraptosis
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting beta-catenin signaling
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 108, 页码: 724-733
作者:
Wang, Jixia
;
Qi, Huan
;
Zhang, Xiuli
;
Si, Wei
;
Xu, Fangfang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/06/20
Triple-negative breast cancer
Saikosaponin D
Radix Bupleuri
Wnt/beta-catenin