中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
高能物理研究所 [9]
合肥物质科学研究院 [6]
深圳先进技术研究院 [5]
大连化学物理研究所 [5]
昆明植物研究所 [4]
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OAI收割 [110]
iSwitch采集 [13]
内容类型
期刊论文 [121]
学位论文 [2]
发表日期
2018 [123]
学科主题
Oncology [2]
Biochemist... [1]
Chemistry [1]
Chemistry,... [1]
Engineerin... [1]
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发表日期:2018
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Apoferritin nanocages loading mertansine enable effective eradiation of cancer stem-like cells in vitro
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018, 卷号: 553, 期号: 1-2, 页码: 201-209
作者:
Tan, Tao
;
Wang, Yuqi
;
Wang, Hong
;
Cao, Haiqiang
;
Wang, Zhiwan
  |  
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2019/01/08
Apoferritin
Mertansine
Cancer stem cells
Breast cancer
Nanocages
Drug delivery
Occurrence, distribution, and ecological-health risks of selected antibiotics in coastal waters along the coastline of China
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 644, 页码: 1469-1476
作者:
Lu, Jian
;
Wu, Jun
;
Zhang, Cui
;
Zhang, Yuxuan
;
Lin, Yichen
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/08
Antibiotics
Ecological risks
Health risk assessment
China coastal waters
Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 48, 页码: 41118-41128
作者:
Chen, Wu
;
Yang, Wen
;
Chen, Pengyu
;
Huang, Yongzhuo
;
Li, Feng
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
disulfiram
copper diethyldithiocarbamate
drug resistance
prostate cancer
nanoparticle
drug delivery
paraptosis
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling
期刊论文
OAI收割
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:
Chen, Jianzhong
;
Peng, Cheng
;
Wang, Jinan
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
allosteric inhibitor
HIV-1 protease
MM-GBSA
normal mode analysis
REMD
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
期刊论文
OAI收割
SMALL, 2018, 卷号: 14, 期号: 47
作者:
Yin, Weimin
;
Yu, Xiaolu
;
Kang, Xuejia
;
Zhao, Yuge
;
Zhao, Pengfei
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
antiangiogenesis
EGFR(T790M) mutation
PD-L1 nanobody
simvastatin
tumor-associated macrophage
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology
期刊论文
iSwitch采集
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18, 页码: 17
作者:
Bing, Zhitong
;
Cheng, Zhiyuan
;
Shi, Danfeng
;
Liu, Xinkui
;
Tian, Jinhui
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/10/09
Systems pharmacology
Fuzhengkangai formula
Herbal medicines
Molecular docking
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology
期刊论文
OAI收割
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
作者:
Bing, Zhitong
;
Cheng, Zhiyuan
;
Shi, Danfeng
;
Liu, Xinkui
;
Tian, Jinhui
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/03/27
Systems pharmacology
Fuzhengkangai formula
Herbal medicines
Molecular docking
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR
期刊论文
OAI收割
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:
Li, R.
;
Du, Y.
;
Shen, J.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
BTK inhibitors
B-cell malignancies
molecule docking
3D-QSAR
CoMFA
CoMSIA
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp
期刊论文
OAI收割
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
作者:
Xie, Xiaoyan
;
Ma, Jing
;
Xu, Min
;
Zhao, Xinjie
;
Gu, Weiqiong
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
bile acid
hyperglycemic clamp
insulin secretion
type 2 diabetes mellitus