中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [118]
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OAI收割 [118]
内容类型
期刊论文 [105]
会议论文 [10]
学位论文 [3]
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2023 [2]
2022 [3]
2021 [4]
2020 [7]
2019 [2]
2018 [7]
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Oncology [2]
Biochemist... [1]
Biophysics [1]
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浏览/检索结果:
共118条,第1-10条
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专题:上海药物研究所
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Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Gut Microbiota Metabolite 3-Indolepropionic Acid Directly Activates Hepatic Stellate Cells by ROS/JNK/p38 Signaling Pathways
期刊论文
OAI收割
BIOMOLECULES, 2023, 卷号: 13, 期号: 10, 页码: 14
作者:
Yuan, Xiaoyan
;
Yang, Junting
;
Huang, Yuling
;
Li, Jia
;
Li, Yuanyuan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
gut-liver axis
3-Indolepropionic acid
HSCs
liver fibrosis
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
Tribulus terrestris L. extract ameliorates atherosclerosis by inhibition of vascular smooth muscle cell proliferation in ApoE(-/-) mice and A7r5 cells via suppression of Akt/MEK/ERK signaling
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 297, 页码: 15
作者:
Zhang, Jing
;
Zhao, Wai-Rong
;
Shi, Wen-Ting
;
Tan, Jun-Jie
;
Zhang, Kai-Yu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Plaque progression
Hyperlipidemia
Mitogen-activated protein kinases
Oxidized low density lipoprotein
VSMC phenotype Switching
Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 8
作者:
Chen, Yan
;
Wang, Chen-yao
;
Zan, Gui-ying
;
Yao, Song-yu
;
Deng, Ying-zhi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/11/11
morphine withdrawal
conditioned place aversion
kappa opioid receptor
p38 MAPK
norBNI
dorsal hippocampus
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
OAI收割
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/12/16
PDPOB Exerts Multiaspect Anti-Ischemic Effects Associated with the Regulation of PI3K/AKT and MAPK Signaling Pathways
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 23, 页码: 4416-4427
作者:
Zhao, Qinyuan
;
Shao, Xingcheng
;
Ding, Xun
;
Lin, Sijin
;
Zhang, Dong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
ischemic stroke
n-pentyl 4-(3,4-dihydroxyphenyl)-4-oxobutanoate
neuroprotection
neuroinflammation
MCAO
Increasing the Sampling Efficiency of Protein Conformational Change by Combining a Modified Replica Exchange Molecular Dynamics and Normal Mode Analysis
期刊论文
OAI收割
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2021, 卷号: 17, 期号: 1, 页码: 13-28
作者:
Peng, Cheng
;
Wang, Jinan
;
Shi, Yulong
;
Xu, Zhijian
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
期刊论文
OAI收割
THERANOSTICS, 2021, 卷号: 11, 期号: 20, 页码: 9821-9832
作者:
Li, Xiaoxun
;
Liang, Yajun
;
Lian, Cheng
;
Peng, Fangli
;
Xiao, Yansen
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/01/04
Breast cancer
Bone metastasis
Osteoclastogenesis
CST6
Peptide drug
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:
Zhang, Shiyan
;
Huang, Chaoying
;
Lyu, Xilin
;
Wang, Peipei
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
ASK1
ASK2
Selectivity
Apoptosis
Cell cycle arrest