机构

• 上海药物研究所 [174]

采集方式

• OAI收割 [174]

内容类型

• 期刊论文 [174]

发表日期

• 2024 [7]
• 2023 [24]
• 2022 [16]
• 2021 [14]
• 2020 [10]
• 2019 [5]
• 更多

学科主题

• Pharmacolo... [3]
• Chemistry [1]
• Immunology [1]
• Integrativ... [1]
• Neuroscien... [1]
• Plant Scie... [1]
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浏览/检索结果: 共174条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Activating CD8+ T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 15 作者:  Wang, Bin;  Zhou, Jingyu;  Li, Ruitong;  Tang, Dongsheng;  Cao, Zheng   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/04/09 chemotherapy  immunotherapy  immunogenic cell death  tumor immune microenvironment   Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database 期刊论文  OAI收割 BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13 作者:  Zhou, Jianxing;  Zheng, You;  Xu, Baohua;  Long, Songjun;  Zhu, Li-e   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/25 GLP-1RAs  Suicidal or self-injurious behaviors  Pharmacovigilance  FAERS database  Type 2 diabetes  Obesity   Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/25 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279 作者:  Zhou, Chenmao;  Hao, Xinyue;  Chen, Zhengyang;  Zhang, Runze;  Zhou, Qian   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/03/13 Speckle-type POZ protein (SPOP)  SPOP inhibitors  Clear cell renal cell carcinoma (ccRCC)  Structure-activityrelationship (SAR)   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12 作者:  Tang, Shuai;  Duan, Yichen;  Yuan, Tao;  Hu, Yutinh;  Yuan, Liang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 KRAS  Pancreatic ductal adenocarcinoma  MAPK pathway  Tetrandrine  TRAIL  Death receptors   Ligand activation mechanisms of human KCNQ2 channel 期刊论文  OAI收割 Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632 作者:  Ma, Demin;  Zheng, Yueming;  Li, Xiaoxiao;  Zhou, Xiaoyu;  Yang, Zhenni   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/26