机构

• 上海药物研究所 [16]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2022 [1]
• 2021 [1]
• 2020 [4]
• 2019 [3]
• 2018 [4]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共16条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119 作者:  Tan, Xiaoqin;  Li, Chunpu;  Yang, Ruirui;  Zhao, Sen;  Li, Fei   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/06/15 Diversified strategy for the synthesis of DNA-encoded oxindole libraries 期刊论文  OAI收割 CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 8, 页码: 2841-2847 作者:  Wang, Xuan;  Liu, Jiaxiang;  Yan, Ziqin;  Liu, Xiaohong;  Liu, Sixiu   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24 Mechanism and optimization of supramolecular complexation-enhanced fluorescence spectroscopy for the determination of SN-38 in plasma and cells 期刊论文  OAI收割 LUMINESCENCE, 2020, 页码: 12 作者:  Zhao, Kena;  Guo, Tao;  Sun, Xian;  Xiong, Ting;  Ren, Xiaohong   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/12/24 cyclodextrins  inclusion complex  pharmacokinetics  SN‐  38  spectrofluorimetric  transfer   Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16 作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong   |  收藏  |  浏览/下载：52/0  |  提交时间：2020/12/21 Schizophrenia  Multitarget antipsychotic drugs  Recurrent neural network  Multitask deep neural network  Automated drug design   Optimizing chemical reaction conditions using deep learning: a case study for the Suzuki-Miyaura cross-coupling reaction 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 16, 页码: 2269-2277 作者:  Fu, Zunyun;  Li, Xutong;  Wang, Zhaohui;  Li, Zhaojun;  Liu, Xiaohong   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 Integrative Proteomic Characterization of Human Lung Adenocarcinoma 期刊论文  OAI收割 CELL, 2020, 卷号: 182, 期号: 1, 页码: 245-+ 作者:  Xu, Jun-Yu;  Zhang, Chunchao;  Wang, Xiang;  Zhai, Linhui;  Ma, Yiming   |  收藏  |  浏览/下载：40/0  |  提交时间：2020/12/24 KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules 期刊论文  OAI收割 BIOINFORMATICS, 2019, 卷号: 35, 期号: 24, 页码: 5354-5356 作者:  Li, Zhaojun;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun;  Xiong, Zhaoping   |  收藏  |  浏览/下载：226/0  |  提交时间：2020/07/01 Deep Neural Network Classifier for Virtual Screening Inhibitors of (S)-Adenosyl-L-Methionine (SAM)-Dependent Methyltransferase Family 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 17 作者:  Li, Fei;  Wan, Xiaozhe;  Xing, Jing;  Tan, Xiaoqin;  Li, Xutong   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 deep neural network  virtual screening  methyltransferase  epigenetic  drug design   Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma 期刊论文  OAI收割 NATURE, 2019, 卷号: 567, 期号: 7747, 页码: 257-+ 作者:  Jiang, Ying;  Sun, Aihua;  Zhao, Yang;  Ying, Wantao;  Sun, Huichuan   |  收藏  |  浏览/下载：62/0  |  提交时间：2020/07/01 Artificial intelligence in drug design 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204 作者:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 drug design  artificial intelligence  deep learning  QSAR  ADME/T