中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2015 [12]
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发表日期:2015
专题:上海药物研究所
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Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1503-1513
作者:
Li, Ting
;
Xu, Xiao-huang
;
Tang, Zheng-hai
;
Wang, Ya-fang
;
Leung, Chung-hang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
platycodin D
human hepatocellular carcinoma
BEL-7402 cells
apoptosis
autophagy
ERK
JNK
U0126
SP600125
chloroquine
BAF
Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1528-1536
作者:
Gao, Zhi-wei
;
Zhu, Yun-ting
;
Yu, Ming-ming
;
Zan, Bin
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
TPN729MA
PDE5 inhibitor
erectile dysfunction
pharmacokinetics
human PK prediction
physiologically based pharmacokinetic model
(Z)3,4,5,4 '-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:
Fan, Xing-Xing
;
Yao, Xiao-Jun
;
Xu, Su Wei
;
Wong, Vincent Kam-Wai
;
He, Jian-Xing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells
期刊论文
OAI收割
Oncology reports, 2015, 卷号: 34, 期号: 3, 页码: 1543-8
作者:
Ye, Yan
;
Chao, Xiao-Juan
;
Wu, Jin-Feng
;
Cheng, Brian Chi-Yan
;
Su, Tao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Application of chemical biology in target identification and drug discovery
期刊论文
OAI收割
ARCHIVES OF PHARMACAL RESEARCH, 2015, 卷号: 38, 期号: 9, 页码: 1642-1650
作者:
Zhu, Yue
;
Xiao, Ting
;
Lei, Saifei
;
Zhou, Fulai
;
Wang, Ming-Wei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Chemical biology
Genomics
Proteomics
Drug discovery
Target validation
High-throughput screening (HTS)
Inhibitory Effects of (2 ' R)-2 ',3 '-dihydro-2 '-(1-hydroxy-1-methylethyl)-2,6 '-bibenzofuran-6,4 '-diol on Mushroom Tyrosinase and Melanogenesis in B16-F10 Melanoma Cells
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2015, 卷号: 29, 期号: 7, 页码: 1040-1045
作者:
Zhu, Jing-jie
;
Yan, Gui-rui
;
Xu, Zhi-jian
;
Hu, Xiao
;
Wang, Gai-hong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
(2 ' R)-2 ' 3 '-dihydro-2 '-(1-hydroxy-1-methylethyl)-2,6 '-bibenzofuran-6,4 '-diol
tyrosinase
inhibitor
melanogenesis
Morus notabilis
Moraceae
Tigliane Diterpenoids from the Euphorbiaceae and Thymelaeaceae Families
期刊论文
OAI收割
CHEMICAL REVIEWS, 2015, 卷号: 115, 期号: 9, 页码: 2975-3011
作者:
Wang, Hong-Bing
;
Wang, Xiao-Yang
;
Liu, Li-Ping
;
Qin, Guo-Wei
;
Kang, Ting-Guo
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
(2S)-7,4 '-dihydroxy-8-prenylflavan stimulates adipogenesis and glucose uptake through p38MAPK pathway in 3T3-L1 cells
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 卷号: 460, 期号: 3, 页码: 578-582
作者:
Ji, Jun
;
Zhu, Jingjie
;
Hu, Xiao
;
Wang, Ting
;
Zhang, Xiaodong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
(2S)-7,4 '-dihydroxy-8-prenylflavan
Adipogenesis
Glucose uptake
p38MAPK
Type 2 diabetes
Dual targeting of microtubule and topoisomerase II by alpha-carboline derivative YCH337 for tumor proliferation and growth inhibition
期刊论文
OAI收割
ONCOTARGET, 2015, 卷号: 6, 期号: 11, 页码: 8960-8973
作者:
Yi, Jun-Mei
;
Zhang, Xiao-Fei
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
YCH337
alpha-carboline derivative
microtubule
topoisomerase II
antitumor activity
G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L
期刊论文
OAI收割
ELIFE, 2015, 卷号: 4
作者:
Zhang, Tao
;
Dong, Kangyun
;
Liang, Wei
;
Xu, Daichao
;
Xia, Hongguang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08