机构

• 上海药物研究所 [22]

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [22]

发表日期

• 2021 [22]

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo   |  收藏  |  浏览/下载：65/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/06/15 Dezocine as a potent analgesic: overview of its pharmacological characterization 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Ye, Rong-Rong;  Jiang, Shuang;  Xu, Xu;  Lu, Yan;  Wang, Yu-Jun   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/12/16 dezocine  opioid receptors  norepinephrine  serotonin transporter  postoperative pain  anesthesia   A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文  OAI收割 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/12/01 DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing 期刊论文  OAI收割 CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+ 作者:  Li, Yufeng;  Xu, Junyu;  Lu, Yuting;  Bian, Hua;  Yang, Lin   |  收藏  |  浏览/下载：49/0  |  提交时间：2022/01/18 The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15 作者:  Fu, Yadong;  Xiao, Zhun;  Tian, Xiaoting;  Liu, Wei;  Xu, Zhou   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/01/04 traditional Chinese medicine  JY5 formula  fuzheng huayu  hepatic fibrosis  notch signaling pathway   Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer 期刊论文  OAI收割 ADVANCED MATERIALS, 2021, 页码: 12 作者:  Zhou, Fengqi;  Gao, Jing;  Tang, Yang;  Zou, Zhifeng;  Jiao, Shi   |  收藏  |  浏览/下载：59/0  |  提交时间：2021/11/04 antigen presentation  autophagy inhibition  immune resistance  immunotherapy  prodrug nanovesicles   Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine   Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483 作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 Acidity-Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer 期刊论文  OAI收割 ADVANCED MATERIALS, 2021, 卷号: 33, 期号: 31, 页码: 2101155 作者:  Song, Rundi;  Li, Tianliang;  Ye, Jiayi;  Sun, Fang;  Hou, Bo   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 cancer immunotherapy  ferroptosis  immune resistance  immunogenic cell death  T lymphocytes