中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2023 [1]
2022 [1]
2021 [1]
2019 [1]
2014 [1]
2013 [1]
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专题:上海药物研究所
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Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Dual-acting antitumor agents targeting the A2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine derivatives
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114326
作者:
Zhang, Jinfeng
;
Luo, Ziwei
;
Duan, Wenwen
;
Yang, Kexin
;
Ling, Lijun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/21
Bifunctional
Structure-based
Cancer
Immunotherapy
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:
Yan, Wenzhong
;
Ling, Lijun
;
Wu, Yiran
;
Yang, Kexin
;
Liu, Ruiquan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
Pharmacologic characterization of fluzoparib, a novel poly(ADP-ribose) polymerase inhibitor undergoing clinical trials
期刊论文
OAI收割
CANCER SCIENCE, 2019, 卷号: 110, 期号: 3, 页码: 1064-1075
作者:
Wang, Lei
;
Yang, Changyong
;
Xie, Chengying
;
Jiang, Jiahua
;
Gao, Mingzhao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
antitumor activity
fluzoparib
pharmacokinetics
poly(ADP-ribose) polymerase
toxicity
Synthesis, anticancer activity and toxicity of a water-soluble 4S,5S-derivative of heptaplatin, cis-{Pt(II)[(4S,5S)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane].(3-hydroxyl-cyclobutane-1,1-dicarboxylate)}
期刊论文
OAI收割
JOURNAL OF INORGANIC BIOCHEMISTRY, 2014, 卷号: 140, 页码: 126-130
作者:
Liu, Weiping
;
Jiang, Jing
;
Xie, Chengying
;
Hou, Shuqian
;
Quan, Haitian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Platinum complexes
Anticancer activity
Toxicity
Heptaplatin
Derivative
cis-[Pt-II(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)], a Water-Soluble, Oxalate-Free and Stable Analogue of Oxaliplatin: Synthesis, Characterization, and Biological Evaluations
期刊论文
OAI收割
CHEMMEDCHEM, 2013, 卷号: 8, 期号: 9, 页码: 1465-1467
作者:
Liu, Weiping
;
Ye, Qingsong
;
Jiang, Jing
;
Lou, Liguang
;
Xu, Yongping
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
antitumor agents
biological activity
oxaliplatin
platinum
synthesis
Synthesis and cytotoxicity of diam(m)ineplatinum(II) complexes with 2,2-bis(hydroxymethyl)malonate as the leaving group
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 6, 页码: 2239-2241
作者:
Xing, Yingjuan
;
Lou, Liguang
;
Chen, Xizhu
;
Ye, Qingsong
;
Xu, Yongping
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
Platinum
2,2-bis(Hydroxymethyl)malonate
Synthesis
Anticancer activity