中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [275]
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OAI收割 [275]
内容类型
期刊论文 [272]
会议论文 [3]
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2024 [4]
2023 [21]
2022 [18]
2021 [26]
2020 [25]
2019 [26]
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浏览/检索结果:
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专题:上海药物研究所
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Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 11
作者:
Wu, Xiaomei
;
Wang, Wenxin
;
Stelitano, Giovanni
;
Riabova, Olga
;
Wang, Bin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Anti -tubercular activity
DprE1 inhibitor
Benzothiazinone derivatives
Structure activity relationship
Revisiting the Role of Valeric Acid in Manipulating Ulcerative Colitis
期刊论文
OAI收割
INFLAMMATORY BOWEL DISEASES, 2024, 页码: 12
作者:
Liu, Moting
;
Zhang, Yao
;
Liu, Jia
;
Xiang, Caigui
;
Lu, Qiukai
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
ulcerative colitis
macrophages
gut microbes
scfas
valeric acid
The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
期刊论文
OAI收割
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32
作者:
Wei, Qing
;
Li, Peijing
;
Yang, Teng
;
Zhu, Jiayu
;
Sun, Lu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
Antibody-drug conjugate
Solid tumor
Combination therapy
Immunotherapy
Targeted therapy
Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer
期刊论文
OAI收割
MATERIALS TODAY BIO, 2023, 卷号: 23, 页码: 16
作者:
Wang, Lu
;
Zhang, Tianyu
;
Zheng, Yile
;
Li, Yuting
;
Tang, Xiyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13
作者:
Zeng, Yue
;
Shi, Wei
;
Liu, Zhi
;
Xu, Hao
;
Liu, Liya
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Elucidation of N-/O-glycosylation and site-specific mapping of sialic acid linkage isomers of SARS-CoV-2 human receptor angiotensin-converting enzyme 2
期刊论文
OAI收割
ANALYST, 2023, 卷号: 148, 期号: 20, 页码: 5002-5011
作者:
Wei, Liming
;
Chen, Yuning
;
Feng, Xiaoxiao
;
Yao, Jun
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14
作者:
Chen, Xi
;
Yang, Jia-bin
;
Cao, Hui-hui
;
Fang, Xiao-chuan
;
Liu, Shan-hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Liang-Ge-San
Dengue virus serotype 2
Heat shock protein 70
Caveolin1
Envelope protein
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Li, Cuixia
;
Wu, Yiran
;
Wang, Wenli
;
Xu, Lu
;
Zhou, Yan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17