中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [128]
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OAI收割 [128]
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期刊论文 [124]
会议论文 [2]
专利 [1]
学位论文 [1]
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2024 [2]
2023 [10]
2022 [13]
2021 [8]
2020 [3]
2019 [11]
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专题:上海药物研究所
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7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
Li, Yaxu
;
Ran, Qiao
;
Duan, Qiuhui
;
Jin, Jiali
;
Wang, Yanjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus
期刊论文
OAI收割
VIRULENCE, 2023, 卷号: 14, 期号: 1, 页码: 2171641
作者:
Chen, Feifei
;
Di, Hongxia
;
Wang, Yanhui
;
Peng, Chao
;
Chen, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Staphylococcus aureus
Sortase A
protein phosphorylation
virulence
A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 14
作者:
Guan, Dongliang
;
Li, Jian
;
Chen, Feifei
;
Li, Jiaqi
;
Bian, Xiaolei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Lipopeptide
Daptomycin derivatives
Multidrug-resistant bacteria
Kynurenine
Hexakynomycin
Preparation and characteristics of a thermosensitive
in
situ
gel loaded with chitosan nanoparticles for optimal ocular delivery of chloramphenicol
期刊论文
OAI收割
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 卷号: 89, 页码: 12
作者:
Huang, Changying
;
Peng, Liyang
;
Xu, Xinqi
;
Lu, Yunshu
;
Wang, Xueting
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/01/16
In situ gels
Chloramphenicol
Nanoparticles
Drug release
Antimicrobial activity
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria
期刊论文
OAI收割
CHEMMEDCHEM, 2023, 卷号: 18, 期号: 9
作者:
Guan, Dongliang
;
Chen, Feifei
;
Shi, Wei
;
Lan, Lefu
;
Huang, Wei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
norvancomycin
glycopeptide antibiotics
single modification
sulfonium
bacterial resistance
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 153
作者:
Zhang, Xu
;
Wang, Yuxiang
;
Zhang, Xi
;
Shen, Yanyan
;
Yang, Kang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 19
作者:
Lu, Yunfu
;
Chen, Feifei
;
Zhao, Qingmin
;
Cao, Qiao
;
Chen, Rongrong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/08
Could IL-25 be a potential therapeutic target for intestinal inflammatory diseases?
期刊论文
OAI收割
CYTOKINE & GROWTH FACTOR REVIEWS, 2023, 卷号: 69, 页码: 43-50
作者:
Chen, Jie
;
Wang, Yingshu
;
Shen, Lan
;
Xiu, Yanfeng
;
Wang, Bing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
IL-25
Type-2 immunity
Inflammatory bowel disease