中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [233]
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OAI收割 [233]
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期刊论文 [230]
会议论文 [2]
专利 [1]
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2023 [7]
2022 [19]
2021 [11]
2020 [11]
2019 [6]
2018 [11]
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浏览/检索结果:
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agents
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 22
作者:
Zhu, Heping
;
Song, Xiaomin
;
Pan, Yihui
;
Li, Ming
;
Chen, Liang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Glioblastoma
Spirocyclic compounds
Drug design
Antiproliferation
Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14
作者:
He, Fei
;
Jiang, Haowen
;
Peng, Chang
;
Wang, Tingting
;
Xiao, Rongrong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2023/10/17
Glucuronyl C5-epimerase
Growth differentiation factor-15
Obesity
Energy expenditure
Ubiquitination
Pharmacological targeting of Axin2 suppresses cell growth and metastasis in colorectal cancer
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 页码: 21
作者:
Cheng, Li-Zhi
;
Huang, Dan-Ling
;
Tang, Zhang-Rui
;
Zhang, Jia-Hao
;
Xiong, Ting
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
colorectal cancer progression
GSK3 beta-Axin2 interaction
small-molecule inhibitor
Snail
beta-Trcp2
Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 8, 页码: 3925-3936
作者:
Wang, Rong
;
Qu, Jingkun
;
Tang, Xueping
;
Zhang, Jiaxin
;
Ou, Ante
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Colorectal cancer
Gambogic acid
Lactoferrin
Liposome
Tumor drug delivery
Guided Isolation of An Uncommon Cembranoid Orthoester, Sarcotortin A, and Three Skeletal Diverse Terpenoids from the Hainan Soft Coral Sarcophyton tortuosum Based on Molecular Networking Strategy
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 12
作者:
Chen, Zi-Hui
;
Yu, Dan-Dan
;
Li, Cong
;
Su, Ming-Zhi
;
Wu, Qihao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
GNPS
Sarcophyton tuotorsum
soft corals
stereochemistry
terpenoids
Hemin protects UVB-induced skin damage through inhibiting keratinocytes apoptosis and reducing neutrophil infiltration
期刊论文
OAI收割
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2023, 卷号: 238, 页码: 11
作者:
Bai, Fang
;
Fan, Chen
;
Lin, Xi
;
Wang, Hao-Yu
;
Wu, Bing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Hemin
Ultraviolet-B
Keratinocytes apoptosis
Neutrophil maturation and mobilization
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Cyclic enhancement of hypoxic microenvironment via an intelligent nanoamplifier for activated NIR-II fluorescence/photoacoustic imaging-guided precise synergistic therapy
期刊论文
OAI收割
MATERIALS TODAY BIO, 2022, 卷号: 17, 页码: 10
作者:
Zheng, Ziliang
;
Chen, Xuejiao
;
Dai, Rong
;
Wu, Shutong
;
Kang, Weiwei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Second near -infrared window
Dual -modal imaging
Activatable NIR-II FL Imaging
Tumor hypoxia
Synergistic tumor therapy
Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
期刊论文
OAI收割
MOLECULAR CELL, 2022, 卷号: 82, 期号: 24, 页码: 4700-+
作者:
Zhou, Qi
;
Hao, Bingbing
;
Cao, Xiaolei
;
Gao, Lin
;
Yu, Zhenyue
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10