中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2022 [2]
2021 [4]
2020 [1]
2018 [2]
2007 [1]
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专题:上海药物研究所
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ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7697-7716
作者:
Zhang, Shurui
;
Chen, Xiaoxu
;
Wu, Chenglin
;
Xu, Hui
;
Xie, Xiong
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
OAI收割
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:
Chen, Yun
;
Ning, Yi
;
Bai, Gang
;
Tong, Linjiang
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
IRAK4
PROTAC
protein degrader
scaffolding role
diffuse large B-cell lymphoma
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
期刊论文
OAI收割
Acta pharmacologica Sinica, 2018
作者:
Chen, Zhuo
;
Tong, Lin-Jiang
;
Tang, Bai-You
;
Liu, Hong-Yan
;
Wang, Xin
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
7 alpha,8 alpha-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities
期刊论文
OAI收割
FITOTERAPIA, 2018, 卷号: 125, 页码: 174-183
作者:
Zheng, Yuan-Dong
;
Bai, Gang
;
Tang, Chunping
;
Ke, Chang-Qiang
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Podocarpus nagi
Type B nagilactone
Cytotoxic activity
Apoptosis
Solubility of silybin in aqueous hydrochloric acid solution
期刊论文
OAI收割
FLUID PHASE EQUILIBRIA, 2007, 卷号: 254, 期号: 1-2, 页码: 204-210
作者:
Bai, Tong-Chun
;
Zhu, Jian-Jun
;
Hu, Jie
;
Zhang, Hua-Li
;
Huang, Cheng-Gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
silybin
hydrochloric acid
solubility
salt effect
pH effect
molecular hydration
ionization