机构

• 上海药物研究所 [14]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2023 [3]
• 2022 [3]
• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2018 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 17 作者:  Wang, Yu-Jun;  Zan, Gui-Ying;  Xu, Cenglin;  Li, Xue-Ping;  Shu, Xuelian   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/02/19 Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034 作者:  Song, Shukai;  Tang, Haotian;  Ran, Ting;  Fang, Feng;  Tong, Linjiang   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 SyntaLinker  Generative modelling  TBK1 inhibitor  pyrrolo[2  3-d]pyrimidine  Structure-activity relationship   Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：80/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations br 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858 作者:  Chen, Hao;  Lai, Mengzhen;  Zhang, Tao;  Chen, Yuqing;  Tong, Linjiang   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858 作者:  Chen, Hao;  Lai, Mengzhen;  Zhang, Tao;  Chen, Yuqing;  Tong, Linjiang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/21 The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma 期刊论文  OAI收割 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2022, 页码: 10 作者:  Ji, Chenxing;  Xu, Wen;  Ding, Hong;  Chen, Zhengyuan;  Shi, Chengzhang   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 p300  A-485  growth hormone pituitary adenoma   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   BRD4 as a therapeutic target for nonfunctioning and growth hormone pituitary adenoma 期刊论文  OAI收割 NEURO-ONCOLOGY, 2020, 卷号: 22, 期号: 8, 页码: 1114-1125 作者:  Shi, Chengzhang;  Ye, Zhao;  Han, Jie;  Ye, Xiaoqing;  Lu, Wenchao   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/21 Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer 期刊论文  OAI收割 CANCER CELL INTERNATIONAL, 2019, 卷号: 19, 期号: 1, 页码: 12 作者:  Qin, Wenyan;  Wang, Xiaodong;  Wang, Yilin;  Li, Yalun;  Chen, Qiuchen   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 H19  Genetic polymorphisms  Susceptibility  Colorectal cancer  Prognosis   Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127 作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang   |  收藏  |  浏览/下载：107/0  |  提交时间：2019/01/08 EGFR(C797s)  Clinical resistance  Fourth-generation nhibitors  Monodrug efficacy