中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [232]
采集方式
OAI收割 [232]
内容类型
期刊论文 [231]
会议论文 [1]
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2024 [2]
2023 [17]
2022 [18]
2021 [26]
2020 [13]
2019 [15]
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Biochemist... [1]
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浏览/检索结果:
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专题:上海药物研究所
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Probing the dynamic thermodynamic resolution and biological activity of Cu(II) and Pd(II) complexes with Schiff base ligand derived from proline
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 4, 页码: 7
作者:
Yu, Tao
;
Soloshonok, Vadim A.
;
Xiao, Zhekai
;
Liu, Hong
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
Schiff bases
Biological activity
Tailor-made amino acids
Asymmetric synthesis
Chiral tridentate ligands
Square-planar Cu(II)-complexes
Square-planar Pd(II)-complexes
A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization
期刊论文
OAI收割
BIOMATERIALS, 2024, 卷号: 304, 页码: 13
作者:
Luo, Lin-Lin
;
Xu, Jie
;
Wang, Bing-Qiao
;
Chen, Chen
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
AAV
Capsid engineering
Phosphosites mutation
Retinal tropism
Neovascularization
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Multiple heart-cutting two-dimensional liquid chromatography/charged aerosol detector assay of ginsenosides for quality evaluation of ginseng from diverse Chinese patent medicines
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2023, 卷号: 1708, 页码: 10
作者:
Xu, Xiao-yan
;
Jiang, Mei-ting
;
Wang, Yu
;
Sun, He
;
Jing, Qi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Multiple heart -cutting two-dimensional liquid
chromatography
Charged aerosol detector
Quantitative assay
Ginseng
Chinese patent medicine
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
αExtractor: a system for automatic extraction of chemical information from biomedical literature
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 4
作者:
Xiong, Jiacheng
;
Liu, Xiaohong
;
Li, Zhaojun
;
Xiao, Hongzhong
;
Wang, Guangchao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
Natural product P57 induces hypothermia through targeting pyridoxal kinase
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Wang, Ruina
;
Xiao, Lei
;
Pan, Jianbo
;
Bao, Guangsen
;
Zhu, Yunmei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/19
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:
Zhang, Yumin
;
Sun, Yuan
;
Xie, Yuanchao
;
Shang, Weijuan
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14
作者:
He, Fei
;
Jiang, Haowen
;
Peng, Chang
;
Wang, Tingting
;
Xiao, Rongrong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2023/10/17
Glucuronyl C5-epimerase
Growth differentiation factor-15
Obesity
Energy expenditure
Ubiquitination
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms