中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2022 [1]
2021 [3]
2019 [2]
2018 [1]
2012 [1]
学科主题
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专题:上海药物研究所
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Dual-acting antitumor agents targeting the A2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine derivatives
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114326
作者:
Zhang, Jinfeng
;
Luo, Ziwei
;
Duan, Wenwen
;
Yang, Kexin
;
Ling, Lijun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
Bifunctional
Structure-based
Cancer
Immunotherapy
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:
Yan, Wenzhong
;
Ling, Lijun
;
Wu, Yiran
;
Yang, Kexin
;
Liu, Ruiquan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP
期刊论文
OAI收割
EMBO JOURNAL, 2019, 页码: 18
作者:
Xu, Zhaowei
;
Zhang, Hainan
;
Zhang, Xingrun
;
Jiang, Hewei
;
Liu, Chengxi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
c-di-GMP
CobB
diguanylate cyclase
negative feedback loop
protein acetylation
Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes (FXRPD)-P-high-L1(low) NSCLC to Anti-PD-1 Immunotherapy
期刊论文
OAI收割
CANCER IMMUNOLOGY RESEARCH, 2019, 卷号: 7, 期号: 6, 页码: 990-1000
作者:
You, Wenjie
;
Li, Lijun
;
Sun, Deqiao
;
Liu, Xueqing
;
Xia, Zongjun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104
作者:
Wang, Yuming
;
Li, Lijun
;
Fan, Jun
;
Dai, Yang
;
Jiang, Alan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Isolation and identification of chemical constituents from leaves of Gynura procumbens(Lour.)Merr.
期刊论文
OAI收割
Journal of Shenyang Pharmaceutical University, 2012, 卷号: 29, 期号: 5, 页码: 337-339
作者:
Zhang Ying
;
Jiang Kun
;
Yang Lijun
;
Tan Junjie
;
Meng Dali
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Gynura procumbens(Lour.)Merr.
chemical constituent
structure identification