中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [84]
上海生物化学与细胞... [30]
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期刊论文 [216]
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Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
Global Profiling of Lysine Acetylation and Lactylation in Kupffer Cells
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2023, 页码: 9
作者:
Sung, Eunji
;
Sim, Hyunchae
;
Cho, Young-Chang
;
Lee, Wonhwa
;
Bae, Jong-Sup
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/11
global proteomics
Kupffer cells
lysine acetylation
lysine lactylation
proteinmodification
Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 11
作者:
Yang, Shuangshuang
;
Fan, Lei
;
Zhang, Rui
;
Song, Chenghuan
;
Shi, Jiyun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Alzheimer's disease
Brain-derived neurotrophic factor
Histone acetylation
Smilagenin
Integrative Profiling of Lysine Acylome in Sepsis-Induced Liver Injury
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2023, 页码: 11
作者:
Na, Ann-Yae
;
Choi, So Young
;
Paudel, Sanjita
;
Bae, Jong-Sup
;
Tan, Minjia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
cecum ligation and puncture model
sepsis
lysine acylation
liver dysfunction
protein modification
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Sulfamethoxazole degradation by Aeromonas caviae and co-metabolism by the mixed bacteria
期刊论文
OAI收割
CHEMOSPHERE, 2023, 卷号: 317, 页码: 10
作者:
Wang, Qiaoning
;
Wang, Hongdan
;
Lv, Min
;
Wang, Xiaoyan
;
Chen, Lingxin
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/08/17
Sulfamethoxazole
Aeromonas caviae GLB-10
Biodegradation
Mixed bacteria
Co-metabolism
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
Guo, Siqi
;
Jia, Tongguan
;
Xu, Xiaoming
;
Yang, Feng
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Global landscape of lysine acylomes in Bacillus subtilis
期刊论文
OAI收割
JOURNAL OF PROTEOMICS, 2023, 卷号: 271, 页码: 12
作者:
Zhang, Mingya
;
Liu, TianXian
;
Wang, Le
;
Huang, Yuqi
;
Fan, Rufeng
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/12/13
Bacillus subtilis
Lysine acetylation
Lysine propionylation
Lysine succinylation
Lysine malonylation
Mass spectrometry
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
期刊论文
OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:
Yang, Zijian
;
Yan, Cong
;
Ma, Jiaqiang
;
Peng, Panpan
;
Ren, Xuelian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10