中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [74]
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:  
Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/03/25
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:  
Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2023/12/08
Deciphering the functional landscape of phosphosites with deep neural network 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 9, 页码: 23
作者:  
Liang, Zhongjie;  Liu, Tonghai;  Li, Qi;  Zhang, Guangyu;  Zhang, Bei
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/12/08
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:  
  |  收藏  |  浏览/下载:14/0  |  提交时间:2023/10/17
Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors 期刊论文  OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:  
Feng, Wenbo;  Zhou, Qingtong;  Chen, Xianyue;  Dai, Antao;  Cai, Xiaoqing
  |  收藏  |  浏览/下载:18/0  |  提交时间:2023/10/17
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:  
Wang, Han-lin;  Li, Jia-nan;  Kan, Wei-juan;  Xu, Gao-ya;  Luo, Guang-hao
  |  收藏  |  浏览/下载:18/0  |  提交时间:2023/10/17
Hypsochromic Shift Donor-Acceptor NIR-II Dye for High-Efficiency Tumor Imaging 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:  
Li, Jiafeng;  Ji, Aiyan;  Lei, Meiling;  Xuan, Liwen;  Song, Ruihu
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
Rhodium(III)-Catalyzed C-H/O2 Dual Activation and Macrocyclization: Synthesis and Evaluation of Pyrido[2,1-a]isoindole Grafted Macrocyclic Inhibitors for Influenza H1N1 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 15
作者:  
Song, Bichao;  Guo, Xueying;  Yang, Li;  Yu, Haiyue;  Zong, Xinlei
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/03/27
Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design 期刊论文  OAI收割
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:  
Gao, Qilin;  Ma, Bingbing;  Wang, Qianwen;  Zhang, Hao;  Fushinobu, Shinya
  |  收藏  |  浏览/下载:4/0  |  提交时间:2024/03/27