机构

• 上海药物研究所 [41]

采集方式

• OAI收割 [41]

内容类型

• 期刊论文 [40]
• 会议论文 [1]

发表日期

• 2023 [1]
• 2022 [3]
• 2021 [1]
• 2020 [1]
• 2019 [3]
• 2018 [6]
• 更多

学科主题

筛选

浏览/检索结果: 共41条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/08/16 P300  Bromodomain inhibitors  CBP30  SBDD   Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15 作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 Epigenetics  p300  CBP  Bromodomain inhibitors  CCS1477   Structure-Based of a Series of NSD2-PWWP1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477 作者:  Li, Na;  Yang, Hong;  Liu, Ke;  Zhou, Liwei;  Huang, Yuting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/21 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing   |  收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Geng et al. reply 期刊论文  OAI收割 CELL RESEARCH, 2020, 页码: 1 作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng;  Zhang, Jing;  Huang, Xun   |  收藏  |  浏览/下载：73/0  |  提交时间：2020/12/24 Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190 作者:  Liu, Ruiqi;  Zhang, Zhuqing;  Yang, Hong;  Zhou, Kaixin;  Geng, Meiyu   |  收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01 p300 inhibitors  Epigenetics  Structure-activity relationship  Sensitive tumor cell proliferation  C646   Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression 期刊论文  OAI收割 CELL RESEARCH, 2019, 卷号: 29, 期号: 10, 页码: 787-803 作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng   |  收藏  |  浏览/下载：83/0  |  提交时间：2020/07/01 Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine gamma-Lyase 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1677-1683 作者:  Hu, Youtian;  Wang, Lu;  Han, Xu;  Zhou, Yueyang;  Zhang, Tonghui   |  收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文  OAI收割 Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842 作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui   |  收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08 1,4-Diaryl-2-azetidinone  Combretastatin A-4  Tubulin polymerization  Antitumor