机构

• 上海药物研究所 [21]

采集方式

• OAI收割 [21]

内容类型

• 期刊论文 [21]

发表日期

• 2024 [1]
• 2023 [5]
• 2022 [4]
• 2021 [2]
• 2020 [1]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共21条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Enzymatic Synthesis of Noncanonical α-Amino Acids Containing γ-Tertiary Alcohols 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 9 作者:  Zhang, Rui;  Zhang, Chenghua;  Tan, Jiamu;  He, Yifan;  Zhuo, Dan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/02/27 Asymmetric Synthesis  Biocatalysis  Noncanonical Amino Acids  Quantum Chemical Calculations  Tertiary Alcohols   PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice 期刊论文  OAI收割 MOLECULAR METABOLISM, 2023, 卷号: 76, 页码: 9 作者:  Bai, Zhonghao;  Yin, Wen;  Liu, Rui;  Tang, Minglei;  Shi, Xiaokeng   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 PRDX1  NASH  Inflammation  Cys52  NF-KB  STAT1   Learning protein fitness landscapes with deep mutational scanning data from multiple sources 期刊论文  OAI收割 CELL SYSTEMS, 2023, 卷号: 14, 期号: 8, 页码: 22 作者:  Chen, Lin;  Zhang, Zehong   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Tora3D: an autoregressive torsion angle prediction model for molecular 3D conformation generation 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 14 作者:  Zhang, Zimei;  Wang, Gang;  Li, Rui;  Ni, Lin;  Zhang, RunZe   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 Conformations generation  Autoregressive  Transformer  Deep learning  Small molecules   Substitution of D-Arginine at Position 11 of & alpha;-RgIA Potently Inhibits & alpha;7 Nicotinic Acetylcholine Receptor 期刊论文  OAI收割 MARINE DRUGS, 2023, 卷号: 21, 期号: 6, 页码: 13 作者:  Wu, Yong;  Zhang, Junjie;  Ren, Jie;  Zhu, Xiaopeng;  Li, Rui   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 conotoxin  peptide synthesis  CD structure  electrophysiology  nicotinic acetylcholine receptors   Drug-Free Biomimetic Oxygen Supply Nanovehicle Promotes Ischemia-Reperfusion Therapy in Stroke 期刊论文  OAI收割 ADVANCED FUNCTIONAL MATERIALS, 2023, 卷号: 33, 期号: 21 作者:  He, Wenxiu;  Zhang, Xiao-Yong;  Gong, Xiang;  Luo, Kuankuan;  Mao, Xuening   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 BBB protection  drug-free biomimetic nanovehicles  hypoxia relief  ischemia-reperfusion therapy  ischemic strokes   Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10 作者:  Song, Jia;  Yang, Rui-rui;  Chang, Jie;  Liu, Ya-dan;  Lu, Cheng-hao   |  收藏  |  浏览/下载：48/0  |  提交时间：2022/11/11 cyclic GMP-AMP synthase  covalent inhibitor  inflammatory bowel disease  high-throughput screening   HSP90 N-terminal inhibitors target oncoprotein MORC2 for autophagic degradation and suppress MORC2-driven breast cancer progression 期刊论文  OAI收割 CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 18 作者:     |  收藏  |  浏览/下载：39/0  |  提交时间：2022/06/15 breast cancer  chaperone-mediated autophagy  HSP90 inhibitor  MORC2  protein degradation   Spiroarborin, an ent-Clerodane Homodimer from Callicarpa arborea as an Inhibitor of the Eleven-Nineteen Leukemia (ENL) Protein by the YEATS Domain 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2022, 卷号: 85, 期号: 2, 页码: 317-326 作者:  Pu, De-Bing;  Guo, Si-Qi;  Ni, Dong-Xuan;  Lin, Jing;  Gao, Jun-Bo   |  收藏  |  浏览/下载：22/0  |  提交时间：2022/06/15 Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2174-2190 作者:  Liu, Liping;  Zhu, Rui;  Li, Jiacheng;  Pei, Yuan;  Wang, Shuangshuang   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/08/16