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上海生物化学与细胞... [34]
上海药物研究所 [6]
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期刊论文 [60]
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Substitution of D-Arginine at Position 11 of & alpha;-RgIA Potently Inhibits & alpha;7 Nicotinic Acetylcholine Receptor
期刊论文
OAI收割
MARINE DRUGS, 2023, 卷号: 21, 期号: 6, 页码: 13
作者:
Wu, Yong
;
Zhang, Junjie
;
Ren, Jie
;
Zhu, Xiaopeng
;
Li, Rui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
conotoxin
peptide synthesis
CD structure
electrophysiology
nicotinic acetylcholine receptors
Synthesis and evaluation of a novel analgesic conotoxin Lt7b that inhibits calcium currents and increases sodium currents
期刊论文
OAI收割
Journal of Cellular and Molecular Medicine, 2022, 卷号: 26, 期号: 20, 页码: 5330-5334
作者:
Wu Y.
;
Yang M.
;
Li Y.
;
Zhang W.
;
Zhou M.
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/11/10
Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond
期刊论文
OAI收割
CHEMICAL SCIENCE, 2020, 卷号: 11
作者:
Zhao, Rui
;
Shi, Pan
;
Chen, Junyou
;
Sun, Shuaishuai
;
Chen, Jingnan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/10/26
Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59
作者:
Qu, Qian
;
Gao, Shuai
;
Wu, Fangming
;
Zhang, Meng-Ge
;
Li, Ying
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/26
chemical protein synthesis
cyclic peptides
disulfides
native chemical ligation
peptides
DISSECTING THE NACHR-INHIBITING D-CONOTOXIN GEXXA
期刊论文
OAI收割
TOXICON, 2019, 卷号: 158, 页码: S26-S26
作者:
Xu, Shaoqiong
;
Yang, Longjin
;
Lv, Aiping
;
Wang, Yanfang
;
Shao, Xiaoxia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/21
Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury
期刊论文
OAI收割
Brain, Behavior, and Immunity, 2018, 卷号: 71, 页码: 52-65
作者:
Jie Yang
;
Man-Xiu Xie
;
Li Hu
;
Xiao-Fang Wang
;
Jie-Zhen Mai
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/06/15
N-type voltage-gated calcium
Dorsal root ganglion
Mechanical allodynia
Excitability
Cytokine
Im10A, a short conopeptide isolated from Conus imperialis and possesses two highly concentrated disulfide bridges and analgesic activity
期刊论文
OAI收割
PEPTIDES, 2016, 卷号: 81, 页码: 15-20
作者:
Yu, Shuo
;
Du, Tianpeng
;
Liu, Zhuguo
;
Wu, Qiaoling
;
Feng, Guixue
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2016/07/12
Conopeptide
Im10A
Isolation
Synthesis
NMR structure
Analgesic activity
Diaminodiacid Bridges to Improve Folding and Tune the Bioactivity of Disulfide-Rich Peptides
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 48, 页码: 14276-14281
作者:
Guo, Ye
;
Sun, De-Meng
;
Wang, Feng-Liang
;
He, Yao
;
Liu, Lei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/10/26
Disulfide-rich Peptide
Peptide Therapeutics
Peptide Synthesis
Protein Engineering
Protein Folding
Identification of Two Novel O2-Conotoxins from Conus generalis
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2015, 卷号: 21, 期号: 1, 页码: 81-89
作者:
Xu, SQ
;
Shao, XX
;
Yan, MD
;
Chi, CW
;
Lu, AP
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2015/07/22
Conotoxin
O2-superfamily
cDNA cloning
gamma-carboxylation
gamma-carboxyglutamic acid
Conus generalis
Prediction of Enzyme's Family Based on Protein-Protein Interaction Network
期刊论文
OAI收割
CURRENT BIOINFORMATICS, 2015, 卷号: 10, 期号: 1, 页码: 16-21
作者:
Niu, Bing
;
Lu, Yin
;
Lu, Jing
;
Chen, Fuxue
;
Zhao, Tonghui
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Amino acid frequency
enzyme family classes
jackknife test
PPI network-based method