机构

• 上海药物研究所 [42]

采集方式

• OAI收割 [42]

内容类型

• 期刊论文 [40]
• 会议论文 [2]

发表日期

• 2023 [6]
• 2022 [5]
• 2021 [2]
• 2020 [5]
• 2019 [3]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共42条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage 期刊论文  OAI收割 CANCER MEDICINE, 2023, 页码: 14 作者:  Chang, Shuaikang;  Xiao, Wenqin;  Xie, Yongsheng;  Xu, Zhijian;  Li, Bo   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 DNA damage  DSBs repair  myeloma  TI17  Trip13   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20 作者:  Sun, Yuting;  Yang, Hui;  Yuan, Jiaqi;  Wang, Limin;  Song, Shanshan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity   Nanolobatone A, An Unprecedented Diterpenoid and Related New Casbanoids from the Hainan Soft Coral Sinularia nanolobata 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 卷号: 29, 期号: 26 作者:  Liu, Jiao;  Li, Song-Wei;  Zhao, Qing-Min;  Zhang, Zai-Yong;  Yao, Li-Gong   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 bioactivity  diterpenoid  Sinularia  soft coral  stereochemistry   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 19 作者:  Hu, Cheng-Long;  Chen, Bing-Yi;  Li, Zijuan;  Yang, Tianbiao;  Xu, Chun-Hui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/13 Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574 作者:  Kayumov, Muzaffar;  Jia, Li;  Pardaev, Azizbek;  Song, Shan-Shan;  Mirzaakhmedov, Sharafitdin   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 PARP1  Olaparib  Alantolactone  Syntheticlethality  BRCA1/2mutant   SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration   Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma 期刊论文  OAI收割 Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1 作者:  Xie,Yongsheng;  Wang,Yingcong;  Xu,Zhijian;  Lu,Yumeng   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15 4-Hydroxysalicylanilid  Ribonucleotide reductase  Deoxyribonucleotides  DNA damage repair  Multiple myeloma