机构

• 上海药物研究所 [61]

采集方式

• OAI收割 [61]

内容类型

• 期刊论文 [61]

发表日期

• 2023 [4]
• 2022 [6]
• 2021 [5]
• 2020 [7]
• 2019 [7]
• 2018 [10]
• 更多

学科主题

筛选

浏览/检索结果: 共61条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng;  Yu, Dongan;  Ren, Hongyuan;  You, Meng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Cryo-EM structures of orphan GPR21 signaling complexes 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1 作者:  Xi Lin;  Bo Chen;  Yiran Wu;  Yingqi Han;  Ao Qi   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 Structures of adenosine receptor A(2B)R bound to endogenous and synthetic agonists 期刊论文  OAI收割 CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 4 作者:  Cai, Hongmin;  Xu, Youwei;  Guo, Shimeng;  He, Xinheng;  Sun, Jun   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1, 页码: 3 作者:  Peng, Jin;  Jiang, Kun;  Sun, Xiao;  Wu, Lingzhi;  Wang, Jiewei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14 作者:  Sun, Haiguo;  Xi, Mengyu;  Jin, Qiang;  Zhu, Zhengdan;  Zhang, Yani   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/09/30 Structural basis for the tethered peptide activation of adhesion GPCRs 期刊论文  OAI收割 NATURE, 2022, 页码: 41 作者:  Ping, Yu-Qi;  Xiao, Peng;  Yang, Fan;  Zhao, Ru-Jia;  Guo, Sheng-Chao   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 Identification of a class of potent USP25 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1 作者:  Jin Peng;  Kun Jiang;  Xiao Sun;  Lingzhi Wu;  Jiewei Wang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/05/22 SAF-248,a novel PI3Kδ-selective inhibitor,potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 209 作者:  Zhang Xi;  Duan Yuting;  Wang Yi;  Zhao Xingdong;  Sun Yiming   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/05/22 PI3K6  PI3K/AKT/mTOR  diffuse large B-cell lymphoma  resistance  combination therapy