机构

• 上海药物研究所 [24]

采集方式

• OAI收割 [24]

内容类型

• 期刊论文 [22]
• 会议论文 [2]

发表日期

• 2023 [2]
• 2022 [1]
• 2020 [2]
• 2019 [1]
• 2018 [3]
• 2017 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共24条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 GRP/GRPR enhances alcohol-associated liver injury through the IRF1-mediated Caspase-1 inflammasome and NOX2-dependent ROS pathway 期刊论文  OAI收割 HEPATOLOGY, 2023, 页码: 17 作者:  Li, Haidi;  Chen, Xin;  Xu, Jiejie;  Zhu, Lin;  Li, Chao   |  收藏  |  浏览/下载：144/0  |  提交时间：2024/02/27 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 19 作者:  Hu, Cheng-Long;  Chen, Bing-Yi;  Li, Zijuan;  Yang, Tianbiao;  Xu, Chun-Hui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/13 Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan   |  收藏  |  浏览/下载：93/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Structural basis of GPBAR activation and bile acid recognition 期刊论文  OAI收割 NATURE, 2020, 页码: 29 作者:  Yang, Fan;  Mao, Chunyou;  Guo, Lulu;  Lin, Jingyu;  Ming, Qianqian   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases 期刊论文  OAI收割 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312 作者:  Liu, Man;  Xiao, Cheng-qian;  Sun, Ming-wei;  Tan, Min-jia;  Hu, Li-hong   |  收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01 covalent interaction  IKK inhibitor  JAK inhibitor  natural compound   Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity 期刊论文  OAI收割 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934 作者:  Xie, Yang;  Zhou, Xu;  Pei, Hu;  Chen, Ming-Cang;  Sun, Zhao-Lin   |  收藏  |  浏览/下载：91/0  |  提交时间：2019/01/08 Modified citrus pectin inhibited bladder tumor growth through downregulation of galectin-3 期刊论文  OAI收割 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1885-1893 作者:  Fang, Tian;  Liu, Dan-Dan;  Ning, He-Ming;  Sun, Jing-Ya;  Huang, Xiao-Jing   |  收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08 7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun   |  收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776 作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 kappa-opioid receptor  mu-opioid receptor  nepenthones  4,5-epoxymorphinans  pharmacological heterogeneity  structure activity relationship  binding structure