中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [13]
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Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:  
Zhu, Ziwei;  Li, Jianing;  Liu, Chong;  Li, Huilin;  Lu, Xingxing
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/04/09
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of Epimedium and Psoraleae Fructus herb pair after oral administration 期刊论文  OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:  
Wang, Linwei;  Yin, Xiaoying;  Liu, Huan;  Wang, Yangyang;  Li, Zhixiong
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/02/27
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:  
Wu, Feifei;  Li, Huiyu;  An, Qi;  Sun, Yaoliang;  Yu, Jinghua
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:  
Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai
  |  收藏  |  浏览/下载:16/0  |  提交时间:2023/04/10
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:  
Zeng, Yue;  Shi, Wei;  Dong, Qian;  Li, Wanzhen;  Zhang, Jianxin
  |  收藏  |  浏览/下载:53/0  |  提交时间:2022/08/30
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats 期刊论文  OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:  
Guo, Zitao;  Liu, Mengling;  Meng, Jian;  Xue, Yaru;  Huang, Qi
  |  收藏  |  浏览/下载:25/0  |  提交时间:2022/08/16
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase 期刊论文  OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:  
Zheng, Yuandong;  Zhang, Hua;  Liu, Mengling;  Li, Guangze;  Ma, Sheng
  |  收藏  |  浏览/下载:23/0  |  提交时间:2022/08/16
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942
作者:  
Zhou, Chuan;  Fan, Zisheng;  Zhou, Zehui;  Li, Yupeng;  Cui, Rongrong
  |  收藏  |  浏览/下载:36/0  |  提交时间:2022/06/15
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 期刊论文  OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:  
Zhu, Yunting;  Li, Liang;  Zhang, Ge;  Wan, Hong;  Yang, Changyong
  |  收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Effect of N-methyl deuteration on metabolism and pharmacokinetics of enzalutamide 期刊论文  OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 卷号: 10, 页码: 2181-2191
作者:  
Jiang, Jinfang;  Pang, Xuehai;  Li, Liang;  Dai, Xiaojian;  Diao, Xingxing
  |  收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08