中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2023 [1]
2022 [2]
2021 [2]
2020 [3]
2018 [3]
2015 [1]
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy
期刊论文
OAI收割
CHEMICAL SCIENCE, 2022, 页码: 8
作者:
Xu, Fang-Zhou
;
Zhu, Ling
;
Han, Hai-Hao
;
Zou, Jian-Wei
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/08/30
Self-Adjuvanting Lipoprotein Conjugate alpha GalCer-RBD Induces Potent Immunity against SARS-CoV-2 and its Variants of Concern
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2558-2570
作者:
Wang, Jian
;
Wen, Yu
;
Zhou, Shi-Hao
;
Zhang, Hai-Wei
;
Peng, Xiao-Qian
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/16
Define Mesenchymal Stem Cell from Its Fate: Biodisposition of Human Mesenchymal Stem Cells in Normal and Concanavalin A-Induced Liver Injury Mice
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 379, 期号: 2, 页码: 125-133
作者:
Han, Li
;
Ma, Chenhui
;
Peng, Huige
;
Wu, Zhitao
;
Xu, Huiming
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/04
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
期刊论文
OAI收割
ACS applied bio materials, 2021, 卷号: 4, 期号: 9, 页码: 7016-7024
作者:
Zhao, Dan
;
Han, Hai-Hao
;
Zhu, Ling
;
Xu, Fang-Zhou
;
Ma, Xing-Yu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/15
aggregation-induced emission (AIE)
mitochondria
photodynamic therapy (PDT)
photosensitizer
theranostic probe
Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 28, 页码: 4
作者:
Wu, Peng
;
Cheng, Tai-Jin
;
Lin, Hai-Xia
;
Xu, Hui
;
Dai, Hui-Xiong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/24
Copper catalyst
C-H activation
Weakly coordinating directing group
Thiolation
Copper-Catalyzed Oxalamide-Directed ortho-C-H Amination of Anilines with Alkylamines
期刊论文
OAI收割
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 13, 页码: 5051-5056
作者:
Wu, Peng
;
Huang, Wei
;
Cheng, Tai-Jin
;
Lin, Hai-Xia
;
Xu, Hui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Chinese medicine CGA formula ameliorates liver fibrosis induced by carbon tetrachloride involving inhibition of hepatic apoptosis in rats
期刊论文
OAI收割
Journal of ethnopharmacology, 2018
作者:
Tian, Huajie
;
Liu, Lin
;
Li, Zhixiong
;
Liu, Wei
;
Sun, Zhaolin
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2019/01/08
From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 44-59
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography