中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [52]
采集方式
OAI收割 [52]
内容类型
期刊论文 [52]
发表日期
2023 [14]
2022 [8]
2021 [5]
2020 [2]
2019 [1]
2018 [2]
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专题:上海药物研究所
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Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 1, 页码: 129-140
作者:
He, Weizhi
;
Yin, Xiaotong
;
Xu, Chu
;
Liu, Xiangyue
;
Huang, Yue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity
期刊论文
OAI收割
SMALL, 2023, 页码: 15
作者:
Yang, Mengdie
;
Liu, Haipeng
;
Lou, Jingjing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
alpha-emitter
immunogenic cell death
pyroptosis
radium-223
stimulator of interferon genes (STING)
Molecular basis of ClC-6 function and its impairment in human disease
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 41, 页码: 15
作者:
Zhang, Bing
;
Zhang, Sensen
;
Polovitskaya, Maya M.
;
Yi, Jingbo
;
Ye, Binglu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Ren, Pengxuan
;
Li, Hui
;
Nie, Tianqing
;
Jian, Xiaoqin
;
Yu, Changyue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Advances in Structure Pharmaceutics from Discovery to Evaluation and Design
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 页码: 26
作者:
Xu, Huipeng
;
Wu, Li
;
Xue, Yanling
;
Yang, Ting
;
Xiong, Ting
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/10/17
structure pharmaceutics
drug delivery systems
three-dimension
quality evaluation
structuredesign
GPCR activation and GRK2 assembly by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 27
作者:
Duan, Jia
;
Liu, Heng
;
Zhao, Fenghui
;
Yuan, Qingning
;
Ji, Yujie
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17