机构

• 上海药物研究所 [89]

采集方式

• OAI收割 [89]

内容类型

• 期刊论文 [89]

发表日期

• 2024 [1]
• 2023 [6]
• 2022 [8]
• 2021 [5]
• 2020 [8]
• 2019 [9]
• 更多

学科主题

筛选

浏览/检索结果: 共89条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma 期刊论文  OAI收割 CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433 作者:  Tao, Hongru;  Jin, Chen;  Zhou, Liyuan;  Deng, Zhenzhong;  Li, Xiao   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/04/09 Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287 作者:  Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/27 The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12 作者:  Zhou, Jiashen;  Zhang, Lin;  Wang, Yiran;  Song, Wenyan;  Huang, Yuzhou   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/12/08 Acyl-ACP Reductases  Allosteric Regulation  Biosynthesis  Enantioselective Reduction  Enzyme Catalysis   Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16 作者:  Yang, Ze-xian;  Zhang, Yu;  Wang, Qing;  Zhang, Lei;  Liu, Yi-fei   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Parkinson's disease  gut-brain axis  a-Synuclein  inflammation  microbiota  intestinal mouse coloclysis model   Elastic network models and molecular dynamic simulations reveal the molecular basis of allosteric regulation in ubiquitin-specific protease 7 (USP7) 期刊论文  OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 162, 页码: 10 作者:  Xu, Jing;  Wang, Yiran;  Zhang, Jiali;  Abdelmoneim, Amr Abbas;  Liang, Zhongjie   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 USP7  Allosteric regulation  Elastic network models  Molecular dynamics simulations   Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24 作者:  Li, Xiao;  Li, Fei;  Ye, Fei;  Guo, Haotian   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 2, 页码: 434 作者:  Chen Jiali;  Feng Zheling;  Zhou Fei;  Lou Ruohan;  Peng Cheng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/05/22 14-deoxygarcinol  adipose tissue inflammation  insulin resistance  interleukin-1β  NLRP3 inflammasome  Sirtuin 2   Chantriolides F-P, Highly Oxidized Withanolides with Hepatoprotective Activity from Tacca chantrieri 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 23, 页码: 18 作者:  Yang, Yue;  Zhou, Fei;  Wang, Min;  Turanazarov, Mukhammadrizo;  Wang, Xiao-Rong   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/04/10 Tacca chantrieri  structural elucidation  withanolides  chantriolides F-P  hepatoprotective effect   Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14 作者:  Huang, Su-Ling;  Xie, Wei;  Ye, Yang-Liang;  Liu, Jia;  Qu, Hui   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/11/11 type 2 diabetes mellitus  coronarin A  glycogen synthesis  gluconeogenesis  mTORC1  IRS1   14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-kappa B/Sirtuin 2-NLRP3-mediated adipose tissue remodeling 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12 作者:  Chen, Jia-li;  Feng, Zhe-ling;  Zhou, Fei;  Lou, Ruo-han;  Peng, Cheng   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/09/30 14-deoxygarcinol  adipose tissue inflammation  insulin resistance  interleukin-1 beta  NLRP3 inflammasome  Sirtuin 2