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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
上海硅酸盐研究所 [6]
金属研究所 [5]
半导体研究所 [4]
合肥物质科学研究院 [2]
中国科学院大学 [1]
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期刊论文 [35]
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Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Effects of wet oxidation on residual stress variation of SiCf/SiC composites
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 8, 页码: 11702-11708
作者:
Wu, Huiyang
;
Guo, Feiyu
;
Yin, Handi
;
Yang, Xinxin
;
Chen, Xiaowu
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
SiCf/SiC composites
Residual stress
Wet oxidation
Raman spectroscopy
Microstructural and mechanical evolution of SiCf/SiC composites in wet oxygen atmosphere above 1000 degrees C
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 6, 页码: 8473-8480
作者:
Guo, Feiyu
;
Chen, Xiaowu
;
Cheng, Guofeng
;
Wu, Huiyang
;
Zhou, Haijun
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Wet-oxygen
SiCf/SiC
Residual stress
Bending strength
Raman spectra
Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228, 页码: 25
作者:
Che, Jinxin
;
Ma, Canliang
;
Lu, Jialiang
;
Chen, Binhui
;
Shi, Qiuqiu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
Seneciobipyrrolidine
Phenotypic screening
Glucose homeostasis
Proteomic analysis
L6 myotubes
4E-BP1
High efficacy of PD-1 inhibitor after initial failure of PD-L1 inhibitor in Relapsed/Refractory classical Hodgkin Lymphoma
期刊论文
OAI收割
BMC CANCER, 2022, 卷号: 22
作者:
Chen, Xi
;
Kong, Haiying
;
Luo, Linxiang
;
Han, Shuiyun
;
Lei, Tao
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/02/14
Hodgkin lymphoma
PD-1 inhibitor
PD-L1 inhibitor
PD-L2
Molecular phenotype
Tumor microenvironment
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
OAI收割
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2022/01/18
Effect of Defects on High Cycle Fatigue Property of Selective Laser Melted Ti6Al4V Alloy
期刊论文
OAI收割
RARE METAL MATERIALS AND ENGINEERING, 2021, 卷号: 50, 期号: 12, 页码: 4429-4436
作者:
Liu Lun
;
Zhang Zhenjun
;
Yang Huajie
;
Ji Haibin
;
Chen Jie
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/07/01
selective laser melting
Ti6Al4V alloy
microstructure
defect
high cycle fatigue property
Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy
期刊论文
OAI收割
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877
作者:
Hu, Shengquan
;
Liu, Jing
;
Chen, Sikang
;
Gao, Jian
;
Zhou, Yubo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
acute myeloid leukemia
FMS-like tyrosine kinase 3
CovDock
hybrid virtual screening
autodock
Effects of interfacial residual stress on mechanical behavior of SiCf/SiC composites
期刊论文
OAI收割
JOURNAL OF ADVANCED CERAMICS, 2021, 页码: 11
作者:
Chen, Xiaowu
;
Cheng, Guofeng
;
Yang, Jinshan
;
Hu, Jianbao
;
Liao, Chunjin
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/12/01
ceramic matrix composites
Raman spectroscopy
mechanical properties
residual stress
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors