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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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高能物理研究所 [170]
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期刊论文 [459]
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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Mid-Holocene pine forest expansion caused by the weakening of the East Asian winter monsoon and linked to climate change in the North Atlantic region
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2023, 卷号: 320, 页码: 10
作者:
Wu, Jing
;
Ren, Wei-he
;
Cui, Qiao-yu
;
Ma, Yu-zhen
;
Marquer, Laurent
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/02
East Asian winter monsoon (EAWM)
Palynology
Mid-Holocene transition
Teleconnection mechanism
Northeast China
Mid-Holocene pine forest expansion caused by the weakening of the East Asian winter monsoon and linked to climate change in the North Atlantic region
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2023, 卷号: 320, 页码: 10
作者:
Wu, Jing
;
Ren, Wei-he
;
Cui, Qiao-yu
;
Ma, Yu-zhen
;
Marquer, Laurent
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/02
East Asian winter monsoon (EAWM)
Palynology
Mid-Holocene transition
Teleconnection mechanism
Northeast China
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Ren, Pengxuan
;
Li, Hui
;
Nie, Tianqing
;
Jian, Xiaoqin
;
Yu, Changyue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2
期刊论文
OAI收割
European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129
作者:
Ren, Pengxuan
;
Yu, Changyue
;
Zhang, Ruxue
;
Nie, Tianqing
;
Hu, Qiaoyu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/26
Rh(III)-Catalyzed Synthesis of Substituted Isoindoles through a Direct C-H Activation/[4+1] Annulation and Acyl Migration Cascade of Oxadiazolones with Diazo Compounds
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 页码: 5
作者:
Yang, Xiaohao
;
Ren, Hairu
;
Zhou, Shengbin
;
Li, Chunpu
;
Liu, Chaoyi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
Responses of East Asian Climate to SST Anomalies in the Kuroshio Extension Region during Boreal Autumn
期刊论文
OAI收割
JOURNAL OF CLIMATE, 2022, 卷号: 35, 期号: 21, 页码: 3407-3423
作者:
Geng, Yu
;
Ren, Hong-Li
;
Ma, Xueying
;
Zhao, Shuo
;
Nie, Yu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/01/04
Atmosphere-ocean interaction
Atmospheric circulation
Climate prediction
An investigation on bloom dynamics of Alexandrium catenella and A. pacificum and toxin accumulation in shellfish along the coast of Qinhuangdao, China
期刊论文
OAI收割
MARINE POLLUTION BULLETIN, 2022, 卷号: 183, 页码: 8
作者:
Tang, Wen-Jiao
;
Lin, Zhuo-Ru
;
Zhang, Qing-Chun
;
Geng, Hui-Xia
;
Sun, Hong-Xiao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
Harmful algal blooms (HABs)
Paralytic shellfish toxins (PSTs)
Alexandrium
qPCR
HPLC-MS/MS
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships