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Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929
作者:
Shen, Donghang
;
Li, Xin
;
Guo, Shimeng
;
Xie, Xin
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
Huntingdon's disease
G protein-coupled receptor
GPR52
alpha-methylene-gamma-butyrolactones
antagonist
Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data Release I
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2023, 卷号: 23, 期号: 7
作者:
Xu, Heng
;
Chen, Siyuan
;
Guo, Yanjun
;
Jiang, Jinchen
;
Wang, Bojun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/07/31
(stars:) pulsars: general
gravitational waves
methods: statistical
methods: observational
Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data Release I
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2023, 卷号: 23, 期号: 7, 页码: 12
作者:
Xu, Heng
;
Chen, Siyuan
;
Guo, Yanjun
;
Jiang, Jinchen
;
Wang, Bojun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/11/14
(stars:) pulsars: general
gravitational waves
methods: statistical
methods: observational
Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data Release I
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2023, 卷号: 23, 期号: 7, 页码: 12
作者:
Xu, Heng
;
Chen, Siyuan
;
Guo, Yanjun
;
Jiang, Jinchen
;
Wang, Bojun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/13
(stars:) pulsars: general
gravitational waves
methods: statistical
methods: observational
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Chen, Lili
;
Yun, Ying
;
Guo, Shimeng
;
Wang, Xiaoyan
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Nucleic acid drug vectors for diagnosis and treatment of brain diseases
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 53
作者:
Lu, Zhi-Guo
;
Shen, Jie
;
Yang, Jun
;
Wang, Jing-Wen
;
Zhao, Rui-Chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/05/19