中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [121]
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期刊论文 [1384]
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PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
VSAN: A new visualization method for super-large-scale academic networks
期刊论文
OAI收割
FRONTIERS OF COMPUTER SCIENCE, 2024, 卷号: 18, 期号: 1, 页码: 19
作者:
Li, Qi
;
Wang, Xingli
;
Fu, Luoyi
;
Cao, Xinde
;
Wang, Xinbing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/09
academic networks
large graph visualization
graph layout
graph loading
Loneliness among older Chinese individuals: the status quo and relationships with activity-related factors
期刊论文
OAI收割
BMC GERIATRICS, 2024, 卷号: 24, 期号: 1, 页码: 11
作者:
Wang, Jiazhou
;
Zhou, Yueyue
;
Zhang, Qiuxia
;
Li, Jing
;
Zhai, Dehua
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/02/15
Chinese older population
Loneliness
Activity ability
Activity participation
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Environmental reconstruction and dating of Shixiakou Locality 1 on China's West Loess Plateau: implications for human adaptive changes apparent during the Last Glacial Maximum (LGM) and post-LGM periods
期刊论文
OAI收割
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES, 2024, 卷号: 16, 期号: 1, 页码: 11
作者:
Li, Feng
;
Zhou, Jing
;
Ren, Jincheng
;
Chen, Fuyou
;
Zhou, Xinying
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/27
Last Glacial Maximum
Northern China
Western Loess Plateau
Microblade technology
Human adaptation
Technological diversity in the tropical-subtropical zone of Southwest China during the terminal Pleistocene: excavations at Fodongdi Cave
期刊论文
OAI收割
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES, 2024, 卷号: 16, 期号: 1, 页码: 23
作者:
Huan, Fa-Xiang
;
Yang, Shi-Xia
;
Gao, Feng
;
Zhou, Xin-Ying
;
Yue, Jian-Ping
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/27
Lithic technology
Southwest China
Terminal Pleistocene
Human adaptation
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Element-dependent evolution of chemical short-range ordering tendency of NiCoFeCrMn under irradiation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PLASTICITY, 2023, 卷号: 171, 页码: 15
作者:
Zhou, Yundi
;
Shi, Tan
;
Li, Jing
;
Wu, Lu
;
Peng Q(彭庆)
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/01
High-entropy alloys
Short-range order
Molecular dynamics
Kinetic Monte Carlo
Irradiation damage
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide