中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
长春光学精密机械与物... [1]
西双版纳热带植物园 [1]
水生生物研究所 [1]
昆明植物研究所 [1]
合肥物质科学研究院 [1]
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采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2020 [14]
学科主题
Biochemist... [2]
Plant Scie... [2]
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浏览/检索结果:
共14条,第1-10条
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发表日期:2020
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Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/beta-catenin pathway regulation in models of Wilson disease
期刊论文
OAI收割
ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9
作者:
Gao, Manli
;
Geng, Hao
;
Wu, Peng
;
Dong, Jianjian
;
Li, Hai
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/30
Wilson disease (WD)
liver injury
Gandou decoction (GDD)
Wnt/beta-catenin pathway
oxidative stress
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
OAI收割
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
BRD4 as a therapeutic target for nonfunctioning and growth hormone pituitary adenoma
期刊论文
OAI收割
NEURO-ONCOLOGY, 2020, 卷号: 22, 期号: 8, 页码: 1114-1125
作者:
Shi, Chengzhang
;
Ye, Zhao
;
Han, Jie
;
Ye, Xiaoqing
;
Lu, Wenchao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/21
Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
期刊论文
OAI收割
CANCER CELL, 2020, 卷号: 37, 期号: 2, 页码: 200-+
作者:
Jiang, Jue
;
Wang, Jingchao
;
Yue, Ming
;
Cai, Xiaolian
;
Wang, Tianci
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/04/23
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
A patent review of BRD4 inhibitors (2013-2019)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81
作者:
Lu, Tian
;
Lu, Wenchao
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Bromodomain-containing protein 4 (BRD4)
bromodomain and extra-terminal (BET) family
small molecule inhibitors
cancer
patent
therapeutic potential
MYC2, MYC3, and MYC4 function additively in wounding-induced jasmonic acid biosynthesis and catabolism
期刊论文
OAI收割
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2020
作者:
Zhang, Cuiping
;
Lei, Yunting
;
Lu, Chengkai
;
Wang, Lei
;
Wu, Jianqiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/01/05