中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [699]
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OAI收割 [699]
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期刊论文 [699]
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共699条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
;
Tao, Yanxin
;
Lin, Guohao
;
Xu, Huiqi
;
Meng, Qingyuan
  |  
收藏
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浏览/下载:0/0
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提交时间:2024/05/22
Diterpenoids from Euphorbia peplus possessing cytotoxic and anti-inflammatory activities
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 14
作者:
Li, Ying
;
Yu, Zhi-Pu
;
Li, Yu-Peng
;
Yu, Jin-Hai
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Euphorbia peplus
Diterpenoids
Cytotoxic activity
Anti-inflammatory activity
NF-kappa B
MAPK
Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
Cephalotane diterpenoids: structural diversity, biological activity, biosynthetic proposal, and chemical synthesis
期刊论文
OAI收割
NATURAL PRODUCT REPORTS, 2024, 页码: 28
作者:
Zhao, Jin-Xin
;
Ge, Zhan-Peng
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:0/0
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提交时间:2024/05/07
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:
Chen, Yuting
;
Wang, Zekun
;
Zhang, Junjie
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
PRMT5
Nucleoside derivatives
Methyltransferases
Structure -activity relationship
Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2024, 卷号: 152, 页码: 12
作者:
Meng, Meiyao
;
Cao, Yuxiang
;
Qiu, Jin
;
Shan, Guangyu
;
Wang, Yingwen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/25
Triglyceride metabolism
ZNF638
Adipose tissue
Angptl8
Lipoprotein lipase
Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism
期刊论文
OAI收割
NATURE REVIEWS ENDOCRINOLOGY, 2024, 页码: 17
作者:
  |  
收藏
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浏览/下载:0/0
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提交时间:2024/05/07
Meta-MolNet: A Cross-Domain Benchmark for Few Examples Drug Discovery
期刊论文
OAI收割
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 15
作者:
Lv, Qiujie
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Benchmark platform
cross-domain meta-learning
drug discovery
few examples
Meta-MolNet
molecular property
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/25
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis