中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [39]
采集方式
OAI收割 [39]
内容类型
期刊论文 [39]
发表日期
2019 [39]
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共39条,第1-10条
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存缴方式:oaiharvest
发表日期:2019
专题:上海药物研究所
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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Common activation mechanism of class A GPCRs
期刊论文
OAI收割
ELIFE, 2019, 卷号: 8, 页码: 31
作者:
Zhou, Qingtong
;
Yang, Dehua
;
Wu, Meng
;
Guo, Yu
;
Guo, Wangjing
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
OAI收割
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 23, 页码: 13
作者:
Shao, Pingxuan
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
pentafluorosulfanyl
aryl propionamide
androgen receptor
agonist
SARMs
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:
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收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity
期刊论文
OAI收割
FITOTERAPIA, 2019, 卷号: 139, 页码: 7
作者:
Feng, Zheling
;
Chen, Shixin
;
Wang, Wei
;
Feng, Lu
;
Dong, Yanyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Lycopodiastrum casuarinoides
Lycopodiaceae
Lycodine-type alkaloids
TD-DFT
ECD
Natural Product Albiziabioside A Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate To Induce Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 19, 页码: 8760-8772
作者:
Wei, Gaofei
;
Sung, Jiahong
;
Luan, Weijing
;
Hou, Zhuang
;
Wang, Shuai
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening
期刊论文
OAI收割
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:
Wan, Fangping
;
Zhu, Yue
;
Hu, Hailin
;
Dai, Antao
;
Cai, Xiaoqing
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/07/01
Deep learning
Machine learning
Drug discovery
In silico drug screening
Compound-protein interaction prediction
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
Integrating yeast chemical genomics and mammalian cell pathway analysis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1245-1255
作者:
Zhou, Fu-lai
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收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
yeast
chemical genomics
tubulin cytoskeleton assembly
autophagy
Wnt/beta-catenin signaling pathway