中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2020 [8]
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共8条,第1-8条
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存缴方式:oaiharvest
发表日期:2020
专题:上海药物研究所
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The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression
期刊论文
OAI收割
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:
Wang, Yingcong
;
Huang, Jing
;
Li, Bo
;
Xue, Han
;
Tricot, Guido
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer
期刊论文
OAI收割
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 8, 页码: 13
作者:
Qin, Yuanyuan
;
Chen, Weilong
;
Jiang, Guojuan
;
Zhou, Lei
;
Yang, Xiaoli
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Inhibition of human thrombin by the constituents of licorice: inhibition kinetics and mechanistic insights through in vitro and in silico studies
期刊论文
OAI收割
RSC ADVANCES, 2020, 卷号: 10, 期号: 7, 页码: 3626-3635
作者:
Shi, Cheng-Cheng
;
Chen, Tian-Ran
;
Zhang, Qi-Hua
;
Wei, Ling-Hua
;
Huang, Chao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Glycolysis is suppressed by DCZ0801-induced inactivation of the Akt/mTOR pathway in Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 16, 页码: 4907-4916
作者:
Feng, Qilin
;
Yao, Qingchun
;
Li, Bo
;
Xie, Yongsheng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
DCZ0801
multiple myeloma
apoptosis
cell cycle
glycolysis